Page 102 - Clinical Application of Mechanical Ventilation
P. 102

68     Chapter 3


                                            gases and to prevent atelectasis. The patient demand and pathology (resistance and
                                            compliance) determines the volume delivered and the spontaneous frequency.

                                            Dual Control within a Breath


                                            Dual control within a breath implies that two variables become control variables
                                            during inspiration within the same breath. During dual control within-a-breath
                                            modes, the ventilator switches from pressure-controlled to volume-controlled. The
                                            clinician sets a desired tidal volume, which becomes a volume target during the
                                            breath. The ventilator begins the breath as a pressure controller, delivering a con-
                                            stant pressure initially during the breath. During breath delivery, tidal volume is
                                            measured and the pressure is adjusted automatically by the ventilator to maintain
                                            the guaranteed tidal volume (volume control). Dual control within-a-breath modes
                                            establish a high initial inspiratory flow (pressure-controlled breath), and a taper or
                                            plateau in flow as the volume target is met. Examples of this mode include pressure
                                            augmentation and volume-assured pressure support.


                                            Dual Control Breath-to-Breath


                                            Dual control breath-to-breath modes allow the clinician to set a volume target,
                                            and the ventilator delivers pressure-controlled breaths attempting to achieve the
                                            desired target tidal volume. The ventilator may operate in either pressure support
                                            or pressure-controlled mode, with the pressure limit increasing or decreasing to
                                            achieve the desired volume target (Branson et al., 2004).

                                            Pressure-Limited Time-Cycled Breaths


                                            Pressure-limited  time-cycled  breaths  begin  inspiration  as  pressure-limited
                                            breaths (pressure increases to a set value or target), and they are time-cycled
                                            (inspiration ends at a specified time interval). The clinician sets a target tidal
                                            volume and maximum pressure (pressure limit). The ventilator delivers a test
                                            breath and calculates the patient’s airway resistance and lung compliance. Once
                                            resistance and compliance have been determined, pressure increases or decreases
                                            automatically to reach the desired volume target. Pressure is adjusted in incre-
                                            ments of 1 to 3 cm H O at a time between breaths, until the maximum pressure
                                                              2
                                            is reached or a set level below the upper pressure limit. If the desired volume is
                                            not met, an alarm alerts the clinician to the fact and the upper pressure limit
                                            is never exceeded. Examples of dual control breath-to-breath pressure-limited,
                                            time-cycled modes include volume control plus (VC1) and pressure-regulated
                                            volume control (PRVC).

                                            Pressure-Limited Flow-Cycled Breaths


                                            Pressure-limited flow-cycled breaths start as a pressure-support breath with a tar-
                                            get tidal volume. Inspiration is flow-cycled (inspiration ends when inspiratory flow






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