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Operating Modes of Mechanical Ventilation  107


                                             time-triggered. Once a breath is triggered, the ventilator tries to reach the pressure
                                             support level as soon as possible. The delivered volume is then compared with the
                                             preset tidal volume for further action by the ventilator.
                                               If the delivered volume equals the preset volume, the breath is considered a pres-
                                             sure support breath. Since pressure support breaths are dependent on the patient
                                             effort, the delivered volume may be larger than the preset volume. It is essential to
                                             set the pressure support level that provides a volume that is lower than the preset
                                             volume. On the other hand, if the delivered volume falls short of the preset volume,
                                             the ventilator switches from a pressure-limited breath to a volume-limited breath.
                                             This results in a longer inspiratory time (at a constant flow) until the preset volume
                            VAPS may prolong the   is delivered.
                          inspiratory time. Patients with
                          airflow obstruction should be   Since VAPS may prolong the inspiratory time automatically, patients with air-
                          monitored closely in order to   flow obstruction should be monitored closely in order to prevent air trapping
                          prevent air trapping and other
                          related side effects.  and other undesirable cardiovascular effects associated with prolonged inspira-
                                             tory time.




                        PRESSURE-REGULATED VOLUME CONTROL (PRVC)



                        pressure-regulated volume   Pressure-regulated volume control (PRVC) is first available in the Siemens 300.
                        control (PRVC): A mode of   Similar modes to PRVC in subsequent ventilators are known as: adaptive pressure
                        ventilation that provides volume-
                        controlled breaths with the lowest   control (Servo-I, Maquet), AutoFlow (Evita XL, Drager), adaptive pressure ven-
                        pressure possible by altering the   tilation (Galileo, Hamilton), volume control 1 (Puritan Bennett, Tyco), volume
                        flow and inspiratory time.
                                             targeted pressure control and pressure controlled volume guaranteed (Engstrom,
                                             General Electric) (Mireles-Cabodevila et al., 2009). In the Siemens 300 ventilator,
                                             PRVC is only active during CMV whereas in other ventilators, this type of dual
                                             control mode is also active in SIMV. Table 4-8 outlines the characteristics of the
                                             PRVC mode.
                                               PRVC is used primarily to achieve volume support while keeping the peak inspira-
                            PRVC provides volume
                          support while keeping the   tory pressure (PIP) at a lowest level possible. This is achieved by altering the peak flow
                          PIP at a lowest level possible
                          by altering the peak flow and   and inspiratory time in response to changing airway or compliance characteristics.
                          inspiratory time in response   For example, Equation (1) shows that at constant flow, the PIP is increased due to
                          to changing airway or compli-
                          ance characteristics.  increasing airflow resistance. Note that the increasing airflow resistance may be due




                                                TABLE 4-8 Characteristics of the Pressure-Regulated Volume Control Mode

                                                Characteristic           Description
                                                Type of breath           CMV in Siemens 300; SIMV in other ventilators

                                                Triggering mechanism     Time-triggered or patient-triggered
                                                Cycling mechanism        Volume-cycled under normal operating
                                                                          conditions
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