Page 330 - Clinical Application of Mechanical Ventilation
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296    Chapter 10


                                             Pulse  contour  analysis  is  not  entirely  noninvasive  because  an  arterial  catheter
                          Pulse contour     is required, and some systems also require a central venous catheter. There are a
                        analysis uses the arterial
                        pressure waveform, arte-  number of monitoring systems based on pulse contour analysis. Since the arterial
                        rial vascular resistance and   pressure waveform varies with changes in arterial compliance, patient condition,
                        patient data to calculate the
                        stroke volume and cardiac   and medications, the systems must be calibrated with another reference standard.
                        output.             Two common reference standards are lithium dilution (Pittman et al., 2005) and
                                            transpulmonary thermodilution (Della et al., 2002).
                                             The Lithium Dilution Cardiac Output (LiDCO) system uses a peripheral venous
                                            catheter into which lithium chloride is injected and then the lithium concentration
                                            is measured at the arterial catheter. The Pulse Contour Cardiac Output (PiCCO)
                                            system uses a combination of the transpulmonary thermodilution technique and ar-
                                            terial pulse contour analysis. Transpulmonary thermodilution is done by injecting a
                                            cold saline solution into a central venous line and then the temperature is measured
                                            at the arterial side (typically via a femoral artery line).
                                             In both LiDCO and PiCCO systems the cardiac output measurement needs to be
                                            repeated on a regular basis and in the occurrence of any changes in patient condi-
                                            tion or fluid and vasoactive drug administration.
                                             The FLOTRAC system does not require calibration with some other method of
                                            measuring cardiac output, but it uses a transducer attached to the patient’s periph-
                                            eral arterial line and interfaced with a special monitor (Vigileo) to measure pulse
                                            pressure. It also uses customized patient data and algorithms to account for changes
                                            in arterial compliance and resistance. The data are updated every 20 seconds and
                                            displayed as a continuous value. This system does not require a central venous line
                                            but there is a specially adapted fiberoptic CVP (PreSep) line which can interface
                                            with the same Vigileo monitor to provide central venous oxygen saturation data
                                              #
                                            (SvO ) to complement the continuous cardiac output data.
                                                2

                      NONINVASIVE HEMODYNAMIC MONITORING



                                            There are three major types of noninvasive hemodynamic monitoring methods:
                                                                                                    #
                                            transesophageal echocardiography, carbon dioxide elimination (VCO ), and im-
                                                                                                        2
                                            pedance cardiography (ICG). Following is a discussion of each technology.

                                            Transesophageal Echocardiography


                                            Transesophageal echocardiography provides diagnosis and monitoring of many
                      transesophageal echocardiog-
                      raphy: A method using a Doppler   structural and functional abnormalities of the heart. It can also be used to calculate
                      transducer in the esophagus for an   cardiac output from measurement of blood flow velocity by recording the Dop-
                      indirect measurement of the blood
                      flow velocity in the descending   pler shift of ultrasound. The time velocity integral obtained for the blood flow in
                      aorta and the calculation of the   the left ventricular outflow tract (e.g., descending aorta) is multiplied by the cross-
                      cardiac output and other hemody-
                      namic data.           sectional area and the heart rate to yield the cardiac output. This Doppler technique
                                            requires a highly skilled technician to obtain accurate readings (Mark et al., 1986).
                                            The transesophageal echocardiography procedure may be done at the bedside, and
                                            continuous readings are available with this procedure. A Doppler transducer probe






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