Page 472 - Clinical Application of Mechanical Ventilation
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438    Chapter 13











                                                           Red

                                              Black
                                                                                                Path of Ulnar Nerve





                                                      PNS




                                                 DBS              Twich
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                                                Tetanus             TOF

                                            Figure 13-5  Placement of the Train-of-Four electrodes along the ulnar nerve.


                                             A clinically useful but less objective method of measuring the depth of blockade
                                            is by assessing the patient’s spontaneous muscle effort. Recovery of muscle blockade
                                            occurs in a reverse sequence. The ability to open one’s eyes widely, sustain head lift,
                          The ability to open eyes   and protrude the tongue for more than 5 sec confirms adequate reversal. Ventila-
                        widely, sustain head lift, and   tor support, however, should not be discontinued until the diaphragm is able to
                        protrude the tongue for more
                        than 5 sec confirms adequate   provide adequate ventilation. Arterial blood gases and spontaneous maneuvers (e.g.,
                        reversal of neuromuscular
                        blockade.           maximal inspiratory pressure [MIP] and vital capacity [VC]) can provide evidence
                                            of partial or full diaphragm recovery (Halloran, 1991). Table 13-11 outlines the
                                            method for assessment of neuromuscular blockade reversal.




                                              TABLE 13-11 Assessment of Neuromuscular Blockade Reversal

                                              1.  Head lift 5 sec

                                              2.  Tongue protrusion 5 sec

                                              3.  Hand grip
                                              4.  Arterial blood gases with PaO  .80 mm Hg and PaCO  ,45 mm Hg*
                                                                                                   2
                                                                             2
                                              5.  Maximal inspiratory pressure (MIP) at least 225 cm H O
                                                                                                  2
                                              6.  Vital capacity greater than 900 mL

                                            *Slightly higher PaCO 2  is acceptable for patients with chronic CO 2  retention.
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