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42  S C O P E   O F   C R I T I C A L   C A R E

         improvement activities or clinical research. In summary,   About 18,000 hospital deaths per year are associated with
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         by  developing,  using  and  evaluating  clinical  practice   AEs  and generally occur as a result of system errors. Half
         guidelines,  nurses  may  improve  patient  care  and  out-  the AEs were deemed preventable with such strategies as
         comes.  Additionally,  use  of  CPGs  should  ensure  that   improved protocols, better-quality monitoring, enhanced
         nursing practice is based on the best available evidence.  training and opportunities to consult with specialists or
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                                                              peers on clinical decisions.  Studies have identified spe-
         QUALITY AND SAFETY MONITORING                        cific  contributing  factors  for  adverse  events  related  to
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                                                              patient airway  and intra-hospital transports. 19
         This section discusses unit-level measures used to evalu-
         ate the quality and safety of care for critically ill patients.   A  number  of  methods  for  reporting  AE  such  as  direct
         Quality and safety in healthcare is commonly described   observation chart audit and self or facilitated reporting
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         in  terms  of  Donabedian’s  approach   with  three  major   can  be  used;  each  has  its  strengths  and  limitations.
         domains:                                             Trained observers report more unintended events but this
                                                              method is expensive, labour intensive and vulnerable to
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            1.  Patient outcomes – the results of care in terms of   the  Hawthorne  effect.   Both  chart  audits  and  incident
               recovery,  restoration  of  function  and/or  survival   reporting  only  reflect  what  is  charted  or  reported,  but
               (e.g. mortality, health-related quality of life).  even when chart audit, incident reporting, general prac-
            2.  Process – the practices involved in the delivery of   titioner reporting and external sources, such as coronial
               care (e.g. pressure ulcer prevention strategies).  review,  are  used  together,  some  adverse  events  will  be
            3.  Structure – the way the healthcare setting and/or   missed.  Importantly, self or facilitated reporting, such as
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               system  is  organised  to  deliver  care  (e.g.  staffing,   the Australian Incident Monitoring Study (AIMS) 22,23  are
               beds, equipment).                              routinely used surveillance methods in many countries.
         More recently, a fourth domain of culture or context has   Medication  administration  is  the  most  common  inter-
         been  suggested  specifically  for  patient  safety  models  to   vention in health care, but the medication management
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         evaluate  the  context  in  which  care  is  delivered.   The   process  in  the  acute  hospital  setting  is  complex,  and
         contemporary model for healthcare improvement recog-  creates  risk  for  patients.  As  a  result,  medication-related
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         nises that the resources (structure) and activities carried   events are the commonest AE for hospitalised patients.
         out (processes) must be addressed within a given context   Adverse  drug  events  (ADEs)  are  common  in  Australian
         (culture) to improve the quality of care (outcome). The   hospitals, with preventable, high-impact events involving
         overall  aim  of  quality  improvement  (QI)  is  to  provide   anticoagulants,  anti-inflammatories  and  cardiovascular
         safe, effective, patient-centred, timely, efficient and equi-  drugs  (over  50%  of  ADEs),  as  well  as  antineoplastics,
                        13
         table health care.  QI activities identify and address gaps   opioids, steroids and antibiotics (commonly used in criti-
         between  knowledge  and  practice.  Importantly,  these   cal care units).  Events are clinically significant in 20%
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         activities need to reflect the most recent and robust clini-  of cases.  A number of strategies have been instituted in
         cal  evidence  to  improve  patient  care  and  reduce  harm.   Australia under the auspices of the National Medicines
         The most common approach used for rapid improvement   Policy,  including  the  quality  use  of  medicines  (QUM)
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         in healthcare is the plan–do–study–act (PDSA)  method   framework. There, however, remains a lack of consensus
         where four essential steps are carried out in a continuous   on how to measure medication safety  – either by error
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         fashion to ensure processes are continually improved:  or adverse event – where:
            1.  Plan – identify a goal, specify aims and objectives   ●  error is a failure in clinical management, resulting in
               to  improving  an  area  of  clinical  practice,  and     potential harm to the patient
               how that might be achieved (i.e. how to test the   ●  adverse events relate to actual patient harm (injury). 17
               intervention).
            2.  Do – implement the plan of action, collect relevant   The  actual  incidence  of  both  measures  is  higher  than
                                                                             17,26
               information that will inform whether the interven-  what is reported.   Fortunately, most healthcare errors
               tion was successful and in what way, taking note   do not result in patient harm because of safety-net pro-
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               of  problems  and  unexpected  observations  that   cesses.   Despite  this,  it  has  been  estimated  that  one
               arise.                                         potentially  serious  intravenous  drug  error  occurs  every
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            3.  Study – the results of the intervention, particularly   day in a 400-bed hospital.  Approximately 5% of medi-
               its  impact  on  practice  improvement,  noting  any   cation  errors  relate  to  infusion  pumps.  These  pumps
               strengths and limitations of the intervention.  are used to administer high-impact medications, such as
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            4.  Act – determine whether the intervention should   inotropes,  heparin  or  antineoplastics.   It  is  therefore
               be  adopted,  abandoned  or  adapted  for  further   important to evaluate interventions that can reduce the
               rapid cycle testing recommencing at the Plan phase.  incidence and impact of adverse intravenous drug events,
                                                              particularly  in  critical  care  settings. 29,30   Recent  evidence
         A variety of specific activities have been used in the ICU   suggests that nurses who are interrupted whilst admini-
         setting to translate findings from the literature to improve   stering medications may have an increased risk of making
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         clinical practice.  Quality monitoring includes measure-  medication  errors,   prompting  calls  for  all  healthcare
         ment of, and response to, the incidence and patterns of   workers to make concerted efforts to reduce interruptions
         adverse events (AEs). Adverse events occur in up to 17%   to  clinical  tasks.   Other  activities  examining  quality
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         of  all  hospital  admissions,   and  cost  the  Australian   of  care  include  the  analysis  of  incident  reports  such  as
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         healthcare  system  an  estimated  $2  billion  per  year.    the  Australian  Incident  Monitoring  Study  (AIMS), 22,23
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