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Quality and Safety 47



                                        stop increased (29 to 63%). PUD prophylaxis 100% at both
                                     Compliance with care bundle: DVT prophylaxis decreased
                                               Mean ventilator days reduced from 10.8 days to 6.1 days
                                      (81 to 71%), HOB >30 °  increased (71 to 83%) & sedation
                                            Mean ICU LOS reduced from 13.75 days to 8.36 days






                                                   ventilated pts increased 39.5% Unit pt throughput increased 30% and no. of invasively   Performance varied widely among & within 13 ICUs Median (ranges): effective assessment of pain 84%  (30–98%); appropriate sedation 64% (2–100%); head of  bed elevation 67% (42–99%); appropriate SUP 89%  (71–98%); appropriate DVT prophylaxis 87% (48–98%) Sig improvement in glucose control (mean of all glucose  measurement reduced from 9.9 ± 4.4 to







                                 Findings  ●   points in time  ●   (P <0.05)  ●   ●   ●   ●   ●   ●







                                     Evaluated impact of a ventilator care  bundle (PUD & DVT prophylaxis, sedation  stop, HOB > 30 ° ) on outcomes Audit data by chart review; compliance  (pre- and post-implementation of care  Measure outcomes over 2 yr study period Only limited improvement in compliance,  other factors could have influenced changes   Compliance of process measures ‘Appropriateness’ of SUP and DVT prophylaxis  not clearly defined or explicitly evaluated Reported resu






                                 Method / Critique  ●   ●   bundle, 7 months apart)  ●   ●  Methods not detailed  ●   in outcomes  ●   ●  No outcome measures  ●   ●   ●   ●   ●  No randomisation  ●   analysis not described  ●  Abbreviations: ICU = intensive care unit; HDU = high dependency unit; QI = quality improvement; CQI = continuous quality improvement; no. = number; b/w = between; yr = year; pts = patients; grp = group; hosp = hospital;  sig = significant; mx = management; mech








                                     Baseline audit n = 21   (pt obs.); Post-   implementation   audit n = 24   Pt outcomes & unit   activity: Pre-test:   286; Post-test: 372  512–602 per yr)



                                 n/cohort                 Not stated  2,764 (range:   over 5 yrs
                              Sample






                                 Setting  6-bed general ICU/  HDU  13 adult medical &   surgical ICUs in   urban teaching   & community   hospitals.  12-bed tertiary   shock/trauma/   respiratory ICU






                                 Design  Retrospective    Prospective, cross-  sectional,   observational  Before/after   quasi-  experimental   with historical   controls  stay; SPC = statistical process control






                                 Study  Crunden   et al. 2005.   (UK) 40  Pronovost   et al. 2003.   (USA) 52  Clemmer   et al. 1999.   (USA) 46
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