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Pregnancy and Postpartum Considerations 721

             should be transferred to a tertiary obstetric centre prior   Antepartum Haemorrhage
             to delivery.
                                                                  Antepartum haemorrhage (APH) is defined as any bleed-
                                                                  ing  from  the  genital  tract  occurring  between  the  20th
                                                                  week of gestation and the birth of the baby and occurs in
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                                                                  2–5% of all pregnancies.  Bleeding from the vagina prior
               Practice tip
                                                                  to 20 weeks’ gestation is referred to in terms of miscar-
               Many maternity professionals abbreviate preeclampsia to PE.   riage (e.g. threatened) and is not classified as an APH. The
               This  can  be  very  confusing  given  that  in  other  health  care    two  main  causes  of  APH  are  placental  abruption  and
               settings,  the  abbreviation  PE  usually  stands  for  pulmonary   placenta praevia.
               embolism. Be clear in any notes that you make, and clarify when
               reading notes that have been given to you.         Placental abruption (or abruptio placentae)
                                                                  Placental abruption is premature separation (i.e. before
                                                                  the birth of the baby) of a normally-sited placenta from
             OBSTETRIC HAEMORRHAGE                                the  uterine  wall  and  is  responsible  for  about  25%  of
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                                                                  APH.  Only a portion of the placenta separates with two-
             Obstetric  haemorrhage  is  a  leading  cause  of  maternal   thirds separation considered severe. There are two rele-
             mortality across the world and directly accounts for an   vant matters to consider with placental abruption: how
             estimated 127,000 deaths each year. Postpartum haemor-  much blood the woman has lost and how much placenta
             rhage  (PPH)  is  responsible  for  the  majority  of  these   remains  attached  and  functionally  able  to  support  the
             maternal deaths. The past decade has seen an increase in   fetus. If the placenta partially separates along an edge of
             both the incidence and severity of obstetric haemorrhage,   the placenta, blood loss is usually visible via the vagina.
             with more women requiring a blood transfusion for post-  In some cases the centre part of the placenta detaches,
             partum haemorrhage than in the past.  Severe bleeding   leaving the rim attached all the way around (like the rim
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             in childbirth is estimated to occur once in every 200–250   of a dinner plate) and in these cases, the blood loss is
             births, although incidence is highly dependent on how   usually  not  visible  via  the  vagina  (i.e.  is  concealed).
             ‘severe  bleeding’  is  defined.   Major  obstetric  haemor-  However,  the  woman  may  have  lost  substantial  blood
                                      24
             rhage is often sudden and unexpected, and is frequently   volume  and  be  in  hypovolaemic  shock.  This  type  of
             associated with an acute coagulopathy. Early recognition   placental  abruption  is  usually  accompanied  by  severe
             and treatment of major obstetric haemorrhage is vital to   abdominal pain and DIC commonly develops in response
             ensure the best outcome for mother and fetus. A repeated   to blood being forced into uterine muscle tissue; referred
             finding in maternal death reviews is a delay by obstetric   to as a couvelaire uterus. Once half to two-thirds of the
             providers in recognising the severity of haemorrhage and   placenta  is  detached,  the  likelihood  of  fetal  survival  is
             a consequent deterioration in maternal condition. 24  low, especially if the woman is also hypotensive. In the
                                                                  majority  of  cases,  only  women  with  severe  placental
             Obstetric  haemorrhage  may  occur  after  the  20th  week
             gestation up to the birth (antepartum haemorrhage) and   abruption  are  admitted  to  ICU  and  usually  admission
             after  the  birth  of  the  baby  (postpartum  haemorrhage).   occurs following an emergency caesarean section. Under-
             Severe  obstetric  haemorrhage  is  a  common  reason    standing  of  the  aetiology  of  placental  abruption  is  not
             for  postpartum  women  to  be  admitted  to  ICU    complete with approximately 20% of cases unexplained.
             at  0.7/1000  deliveries,  with  many  women  experiencing   For most women, placental abruption is associated with
                                                              3
             haemorrhage  before  and  after  the  birth  of  the  baby.    a known related factor like preeclampsia, blunt trauma
             Although  not  classified  technically  as  an  obstetric     (e.g.  car  crash)  and  sudden  reduction  in  uterine
             haemorrhage,  ruptured  ectopic  pregnancy  can  also     volume  (e.g.  after  delivery  of  the  first  baby  in  a  twin
             result  in  life-threatening  haemorrhage  and  result  in     pregnancy).
             ICU  admission.  The  common  causes  of  antepartum    Placenta praevia
             and postpartum haemorrhage are described below with
             common management strategies presented at the end of   Placenta praevia is when some or the entire placenta is
             the section. See also Box 26.4.                      abnormally sited in the lower segment of the uterus, often
                                                                  referred  to  as  a  low-lying  placenta.  Placenta  praevia  is
                                                                  graded into four categories of severity according to the
                                                                  location  of  the  placenta  in  relation  to  the  cervix  (Box
                                                                  26.5). A vaginal birth is not possible with Grades III and
               BOX 26.4  What about vaginal bleeding              IV as the placenta blocks the passage for the baby, neces-
               before the 20th week of gestation?                 sitating  a  caesarean  section.  The  lower  uterine  segment
                                                                  does not fully form until 28–32 weeks’ gestation and the
               Vaginal bleeding before the 20th week of gestation (usually a   shearing stress as the lower uterine segment forms may
               type of miscarriage, e.g. threatened, incomplete) is considered   precipitate detachment of the placenta from the uterine
               ‘early pregnancy bleeding’ and is not categorised as obstetric   wall causing maternal bleeding. However, bleeding can
               hae morrhage per se. Septic abortion (or miscarriage) can cause   occur at any time, is usually painless and may be massive.
               profound bleeding in the days after the event when the infec-  Placenta praevia is the main cause of APH accounting for
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               tion has become established.                       30% of cases.  As with placental abruption, management
                                                                  is  dictated  by  the  size  of  the  blood  loss  and  maternal
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