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1086 Part VIII: Monocytes and Macrophages Chapter 68: Production, Distribution, and Activation of Monocytes and Macrophages 1087

Figure 68–10. Schema of states of monocyte-macrophage activation. AM, alternative M2A; CM, classical (M) activation; DM, M2C deactivated; NPM,
nonpolarized. Membrane markers expression in yellow. Flow cytometry and cytokines enzyme-linked immunosorbent assay (ELISA) in blue. IFN-γ,
interferon-γ; IL, interleukin; LPS, lipopolysaccharide; NK, natural killer; Th1/Th2, T-helper type 1/2; T , T regulatory cell. (Used with permission of S. Seif,
REG
GraphisMedica, 2014.)

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