Page 1593 - Williams Hematology ( PDFDrive )
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1568 Part XI: Malignant Lymphoid Diseases <CN>: <ct> PB
17. Nearman ZP, Wlodarski M, Jankowska AM,: Immunogenetic factors determining the 45. Abkowitz JL, Kadin ME, Powell JS, Adamson JW: Pure red cell aplasia: Lymphocyte inhi-
evolution of T-cell large granular lymphocyte leukaemia and associated cytopenias. Br J bition of erythropoiesis. Br J Haematol 63:59–67, 1986.
Haematol 136:237–248, 2007. 46. Abkowitz JL, Powell JS, Nakamura JM, et al: Pure red cell aplasia: Response to therapy
18. Zambello R, Facco M, Trentin L, et al: Interleukin-15 triggers the proliferation and cyto- with anti-thymocyte globulin. Am J Hematol 23:363–371, 1986.
toxicity of granular lymphocytes in patients with lymphoproliferative disease of granular 47. Lai DW, Loughran TP Jr, Maciejewski JP, et al: Acquired amegakaryocytic thrombocy-
lymphocytes. Blood 89:201–211, 1997. topenia and pure red cell aplasia associated with an occult large granular lymphocyte
19. Zambello R, Trentin L, Cassatella MA, et al: IL-12 is involved in the activation of CD3+ leukemia. Leuk Res 32:823–827, 2008.
granular lymphocytes in patients with lymphoproliferative disease of granular lympho- 48. Bareau B, Rey J, Hamidou M, et al: Analysis of a French cohort of patients with large gran-
cytes. Br J Haematol 92:308–314, 1996. ular lymphocyte leukemia: A report on 229 cases. Haematologica 95:1534–1541, 2010.
20. Epling-Burnette PK, Liu JH, Catlett-Falcone R, et al: Inhibition of STAT3 signaling leads 49. Loughran TP Jr, Hammond WP: Adult-onset cyclic neutropenia is a benign neoplasm
to apoptosis of leukemic large granular lymphocytes and decreased MCL-1 expression. J associated with clonal proliferation of large granular lymphocytes. J Exp Med 164:
Clin Invest 107:351–362, 2001. 2089–2094, 1986.
21. Schade AE, Powers JJ, Wlodarski MW, Maciejewski JP: Phosphatidylinositol-3-phosphate 50. Zambello R, Trentin L, Agostini C, et al: Persistent polyclonal lymphocytosis in human
kinase pathway activation protects leukemic large granular lymphocytes from undergo- immunodeficiency virus-1-infected patients. Blood 81:3015–3021, 1993.
ing homeostatic apoptosis. Blood 107:4834–4840, 2006. 51. Khan S, Myers K: Persistence of natural killer (NK) cell lymphocytosis with hypo-
22. Shah MV, Zhang R, Irby R, et al: Molecular profiling of LGL leukemia reveals role of splenism without development of leukaemia. BMC Clin Pathol 5:8, 2005.
sphingolipid signaling in survival of cytotoxic lymphocytes. Blood 112:770–781, 2008. 52. Qiu ZY, Xu W, Li JY: Large granular lymphocytosis during dasatinib therapy. Cancer Biol
23. Jerez A, Clemente MJ, Makishima H, et al: Stat3 mutations unify the pathogenesis of Ther 15:247–255, 2014.
chronic lymphoproliferative disorders of NK cells and T-cell large granular lymphocyte 53. Rossi D, Franceschetti S, Capello D, et al: Transient monoclonal expansion of CD8+/
leukemia. Blood 120:3048–3057, 2012. CD57+ T-cell large granular lymphocytes after primary cytomegalovirus infection. Am J
24. Koskela HL, Eldfors S, Ellonen P, et al: Somatic STAT3 mutations in large granular lym- Hematol 82:1103–1105, 2007.
phocytic leukemia. N Engl J Med 366:1905–1913, 2012. 54. Wolniak KL, Goolsby CL, Chen YH, et al: Expansion of a clonal CD8+CD57+ large gran-
25. Rajala HL, Eldfors S, Kuusanmaki H, et al: Discovery of somatic STAT5b mutations in ular lymphocyte population after autologous stem cell transplant in multiple myeloma.
large granular lymphocytic leukemia. Blood 121:4541–4550, 2013. Am J Clin Pathol 139:231–241, 2013.
26. Teramo A, Gattazzo C, Passeri F, et al: Intrinsic and extrinsic mechanisms contribute to 55. Boudewijns M, van Dongen JJ, Langerak AW: The human androgen receptor X-chromo-
maintain the JAK/STAT pathway aberrantly activated in T-type large granular lympho- some inactivation assay for clonality diagnostics of natural killer cell proliferations. J Mol
cyte leukemia. Blood 2013;121:3843–3854, S3841. Diagn 9:337–344, 2007.
27. Zhang R, Shah MV, Yang J, et al: Network model of survival signaling in large granular 56. Inghirami G, Zhu BY, Chess L, Knowles DM: Flow cytometric and immunohistochem-
lymphocyte leukemia. Proc Natl Acad Sci U S A 105:16308–16313, 2008. ical characterization of the gamma/delta T-lymphocyte population in normal human
28. Fehniger TA, Suzuki K, Ponnappan A, et al: Fatal leukemia in interleukin 15 transgenic lymphoid tissue and peripheral blood. Am J Pathol 136:357–367, 1990.
mice follows early expansions in natural killer and memory phenotype CD8+ t cells. J 57. Belhadj K, Reyes F, Farcet JP, et al: Hepatosplenic gammadelta T-cell lymphoma is a
Exp Med 193:219–231, 2001. rare clinicopathologic entity with poor outcome: Report on a series of 21 patients. Blood
29. Mishra A, Liu S, Sams GH, et al: Aberrant overexpression of IL-15 initiates large granu- 102:4261–4269, 2003.
lar lymphocyte leukemia through chromosomal instability and DNA hypermethylation. 58. Lu CL, Tang Y, Yang QP, et al: Hepatosplenic T-cell lymphoma: Clinicopathologic,
Cancer Cell 22:645–655, 2012. immunophenotypic, and molecular characterization of 17 Chinese cases. Hum Pathol
30. Chen X, Bai F, Sokol L, et al: A critical role for DAP10 and DAP12 in CD8+ T cell-mediated 42:1965–1978, 2011.
tissue damage in large granular lymphocyte leukemia. Blood 113:3226–3234, 2009. 59. Lamy T, Loughran TP Jr: How I treat LGL leukemia. Blood 117:2764–2774, 2011.
31. Morice WG, Kurtin PJ, Tefferi A, Hanson CA: Distinct bone marrow findings in T-cell 60. Dearden CE, Johnson R, Pettengell R, Devereux S, et al: British Committee for Standards in
granular lymphocytic leukemia revealed by paraffin section immunoperoxidase stains Haematology: Guidelines for the management of mature T-cell and NK-cell neoplasms
for CD8, TIA-1, and granzyme B. Blood 99:268–274, 2002. (excluding cutaneous T-cell lymphoma). Br J Haematol 153:451–485, 2011.
32. Agnarsson BA, Loughran TP Jr, Starkebaum G, Kadin ME: The pathology of large gran- 61. Loughran TP Jr, Kidd PG, Starkebaum G: Treatment of large granular lymphocyte leuke-
ular lymphocyte leukemia. Hum Pathol 20:643–651, 1989. mia with oral low-dose methotrexate. Blood 84:2164–2170, 1994.
33. Freud AG, Zhao S, Wei S, et al: Expression of the activating receptor, NKp46 (CD335), in 62. Osuji N, Matutes E, Tjonnfjord G, et al: T-cell large granular lymphocyte leukemia: A report
human natural killer and T-cell neoplasia. Am J Clin Pathol 140:853–866, 2013. on the treatment of 29 patients and a review of the literature. Cancer 107:570–578, 2006.
34. Gentile TC, Uner AH, Hutchison RE, et al: CD3+, CD56+ aggressive variant of large 63. Sood R, Stewart CC, Aplan PD, et al: Neutropenia associated with T-cell large granular
granular lymphocyte leukemia. Blood 84:2315–2321, 1994. lymphocyte leukemia: Long-term response to cyclosporine therapy despite persistence
35. Lima M, Almeida J, Dos Anjos Teixeira M, et al: TCRalphabeta+/CD4+ large granu- of abnormal cells. Blood 91:3372–3378, 1998.
lar lymphocytosis: A new clonal T-cell lymphoproliferative disorder. Am J Pathol 163: 64. Lamy T, LePrise PY, Amiot L, et al: Response to granulocyte-macrophage colony-
763–771, 2003. stimulating factor (GM-CSF) but not to g-csf in a case of agranulocytosis associated with
36. Bourgault-Rouxel AS, Loughran TP Jr, Zambello R, et al: Clinical spectrum of gamma- large granular lymphocyte (LGL) leukemia. Blood 85:3352–3353, 1995.
delta+ T cell LGL leukemia: Analysis of 20 cases. Leuk Res 32:45–48, 2008. 65. Kaneko T, Ogawa Y, Hirata Y, et al: Agranulocytosis associated with granular lymphocyte
37. Lundell R, Hartung L, Hill S, et al: T-cell large granular lymphocyte leukemias have mul- leukaemia: Improvement of peripheral blood granulocyte count with human recombi-
tiple phenotypic abnormalities involving pan-T-cell antigens and receptors for MHC nant granulocyte colony-stimulating factor (G-CSF). Br J Haematol 74:121–122, 1990.
molecules. Am J Clin Pathol 124:937–946, 2005. 66. Thomssen C, Nissen C, Gratwohl A, et al: Agranulocytosis associated with t-gamma-
38. Morice WG, Kurtin PJ, Leibson PJ, et al: Demonstration of aberrant T-cell and natural lymphocytosis: No improvement of peripheral blood granulocyte count with human-
killer-cell antigen expression in all cases of granular lymphocytic leukaemia. Br J recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF). Br J Haematol
Haem atol 120:1026–1036, 2003. 71:157–158, 1989.
39. Loughran TP Jr, Starkebaum G, Kidd P, Neiman P: Clonal proliferation of large granular 67. Ru X, Liebman HA: Successful treatment of refractory pure red cell aplasia associated
lymphocytes in rheumatoid arthritis. Arthritis Rheum 31:31–36, 1988. with lymphoproliferative disorders with the anti-CD52 monoclonal antibody alemtu-
40. Schrenk KG, Krokowski M, Feller AC, et al: Clonal T-LGL population mimicking leuke- zumab (Campath-1H). Br J Haematol 123:278–281, 2003.
mia in Felty’s syndrome—Part of a continuous spectrum of T-LGL proliferations? Ann 68. Pandolfi F, Loughran TP Jr, Starkebaum G, et al: Clinical course and prognosis of the
Hematol 92:985–987, 2013. lymphoproliferative disease of granular lymphocytes. A multicenter study. Cancer
41. Poullot E, Zambello R, Leblanc F, et al: Chronic natural killer lymphoproliferative disorders: 65:341–348, 1990.
Characteristics of an international cohort of 70 patients. Ann Oncol 25:2030–2035, 2014. 69. Loughran TP Jr: Clonal diseases of large granular lymphocytes. Blood 82:1–14, 1993.
42. Cheung MM, Chan JK, Wong KF: Natural killer cell neoplasms: A distinctive group of 70. Dhodapkar MV, Li CY, Lust JA, et al: Clinical spectrum of clonal proliferations of
highly aggressive lymphomas/leukemias. Semin Hematol 40:221–232, 2003. T-large granular lymphocytes: A T-cell clonopathy of undetermined significance? Blood
43. Sokol L, Loughran TP Jr: Large granular lymphocyte leukemia. Oncologist 11:263–273, 84:1620–1627, 1994.
2006. 71. Semenzato G, Zambello R, Starkebaum G, et al: The lymphoproliferative disease of gran-
44. Lacy MQ, Kurtin PJ, Tefferi A: Pure red cell aplasia: Association with large granular ular lymphocytes: updated criteria for diagnosis. Blood 89:256–260, 1997.
lymphocyte leukemia and the prognostic value of cytogenetic abnormalities. Blood 87: 72. Neben MA, Morice WG, Tefferi A: Clinical features in T-cell vs. natural killer-cell vari-
3000–3006, 1996. ants of large granular lymphocyte leukemia. Eur J Haematol 71:263–265, 2003.
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