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574 Part VI: The Erythrocyte Chapter 40: Paroxysmal Nocturnal Hemoglobinuria 575
Anti-DAF (CD55) Anti-MIRL (CD59)
PNH II PNH II
100
90
80
80
70
60
60
Cell count Cell count 40
PNH 50
40
30 PNH I
PNH III PNH I PNH III
20 20
10
0 0
10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4
Log fluorescence Log fluorescence
60
30
50
Cell count 20 40
NL Cell count 30
10 20
10
0 0
10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4
A Log fluorescence Log fluorescence
Anti-DAF (CD55) Anti-MIRL (CD59)
II
100
90
80
80
70
60 Discrete
Cell count Cell count 40
60
PNH 50 PIGA
40
30 I mutations
III
20 20
10
0 0
10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4
Log fluorescence Log fluorescence
60
30
50
Cell count Cell count 30
NL 20 40
10 20
10
0 0
10 0 10 1 10 2 10 3 10 4 10 0 10 1 10 2 10 3 10 4
B Log fluorescence Log fluorescence
Kaushansky_chapter 40_p0571-0582.indd 574 9/17/15 6:22 PM
