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CHaPtEr 92  Flow Cytometry          1251.e1


              MU lt IP l E-CHOICE QUES t IO n S

           1.  In flow cytometry compensation refers to a process that:   A. Dedicator of cytokinesis 8 (DOCK8) deficiency
              A. Distinguishes between leukocyte populations         B. CD40 ligand deficiency
              B. Eliminates overlapping fluorescent light signals    C. Severe combined immunodeficiency
              C. Provides the level of the cellular autofluorescence   D. Wiskott-Aldrich syndrome
              D. Converts analog light signals into digital signals
                                                                  4.  Which test would be indicated in a child with persistent
           2.  A flow cytometry setup with a combination of five different   systemic nontuberculous infection not responsive to multiagent
             monoclonal reagents, each with a different fluorochrome,   antimicrobial drugs?
             generates how many potential cell subsets?              A. Dihydrorhodamine (DHR) assay
              A. 8                                                   B. Expression of CD18 on granulocytes
              B. 16                                                  C. Level of T-helper-1 (Th1) cell–based on intracellular
              C. 32                                                    interferon-γ (IFN-γ) expression
              D. 64                                                  D. Expression of the IFN-γ receptor type 1 on monocytes
                                                     3
           3.  The finding of a CD3 cell count of 285/mm  and no
             CD4/CD45RA cells in an infant is most consistent with which
             diagnosis?
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