Page 265 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHAPTEr 16 Helper T-Cell Subsets and Control of the Inflammatory Response 245.e1

MULTIPLE-CHOICE QUESTIONS

1. Which of the following is the earliest manifestation of a T-cell D. Tregs can be generated outside of the thymus.
response? E. Tregs help promote homeostasis.
A. Cytokine release 3. A patient arrives in the clinic with a history of recurrent
B. Activation and proliferation infection by Staphylococcus bacteria. Laboratory tests indicate
C. T-cell help that the patient has low serum immunoglobulin G (IgG)
D. T-cell migration levels and reduced numbers of memory B cells in blood.
E. Stimulation of inflammation
What T-cell population is likely impaired?
2. Which of the following is NOT true about regulatory T cells A. CD8 T cells
(Tregs)? B. T-helper (Th)1 effector T cells
A. Tregs express the transcription factor FoxP3. C. Th2 effector T cells
B. Tregs control immune responses by lysing effector CD4 D. Regulatory T cells (Tregs)
T cells. E. T-follicular helper (Tfh) cells
C. Tregs are defective in patients with autoimmune polyendo-
crinopathy–candidiasis–ectodermal dystrophy (APECED).