Page 785 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPtEr 55 Scleroderma–Systemic Sclerosis 755.e1

MUL t IPLE-CHOICE QUES t IONS

1. Which of the following complications is MOST frequent in 3. Which of the scleroderma related autoantibodies are associated
systemic sclerosis (SSc)? with the highest risk for developing a scleroderma renal crisis
A. Glomerulonephritis (SRC)?
B. Scleritis A. Anticentromere
C. Renal crisis B. Antitopoisomerase
D. Tendon rupture C. Anti-RNA polymerase III
E. Pulmonary arterial hypertension D. Anti-U1 ribonucleoprotein (RNP)
E. Anti-U3 RNP
2. Characteristic thoracic involvement in SSc include all of the
following EXCEPT: F. Anti-U11/U12 RNP
A. Pulmonary fibrosis 4. What is the major cause of mortality in scleroderma in the
B. Apical nodules modern era?
C. Peripheral reticulations A. Scleroderma renal crisis
D. Enlarged pulmonary artery B. Severe skin disease
E. Patulous esophagus C. Scleroderma lung disease
D. Gastrointestinal failure
E. Complications of medications