Page 345 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 17 ■ Hemoglobinopathies and Thalassemias 329

■ C mm H SC
NOTE: This is a good time to complete end of chapter β- m (S β- m ).

Review Questions.
■ I U S , m % A
Am .

■ A
CHAP ER HIGHLIGH S m k . A m

, k k

Hemoglobin Defects .

■ D k -
■ A m m m m m , m . T

m . SCD q H S

■ P m m m z - .

z .

■ T k m m C, E, D,

SC, SE, SD . Thalassemia

■ I m S, m T m m m m mm

m m m ■ m . T m

x m

m . m - .

k T m m

x m S m z m ■ m -

m m - , f mRNA,

m m x , ,

x . .

■ A m S m C m m : m j

m ■ m . T

m .

. β T m m mm -

■ I m m C, m m ■ . M β-

m x k β- ,

m . x m

■ H m m m m - γ- , ,

. A x m % m m- .

z α m z

m . ■ α . α m

■ T mm m m -

m m

m . .

■ I m ,

m . A

m z Other Hemoglobinopathies

m -

z , m m - ■ H C m

. A z m H S ( k ) .

m m . ■ H E q
S A . I m T , q

Sickle Cell Disease (Sickle Cell Anemia) H E m %.
■ M m m

■ SCD z H S, m , m m .
m ■ U m m

k m m k -

. m

■ SCD (H SS), m mm m m - m m .
, x k ■ H H F

m . O k m z m m -

k . .