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CHAPTER 28  ■  Disorders of Hemostasis and Thrombosis: Blood Coagulation Factors, Hypercoagulable State, and Anticoagulant Therapy                                                                 581







                                 REVIEW QUESTIONS (continued)





                        *8.  Te ha    ark o  secon  ary   brino ysis is the   resence o                                          15.  Pregnancy can cause a

                             A.   brin s   it   ro  ucts                                                                               A.    ri  ary hy  ercoagu ab e state

                             B.   brin   egra  ation   ro  ucts                                                                        B.  secon  ary hy  ercoagu ab e state

                             C.   brin   ono  ers

                             D.  a   o  the above                                                                              *16.  A characteristic o  circu ating anticoagu ants is which
                                                                                                                                       o  the  o  owing?


                         9.  DIC is characterize   by                                                                                  A.  T e   ost co    on s  eci  c  actor inhibitor

                             A.   icrovascu ar thro  bosis                                                                             B.  Acquire   inhibitors o  c otting   roteins

                             B.   brin   e  osition                                                                                    C.  A so known as anti  hos  ho i  i   or anticar  io i  in

                             C.  active   brino ysis                                                                                   D.  None o  the above

                             D.  a   o  the above                                                                              *17.  A characteristic o   u  us anticoagu ant is which o  the


                                                                                                                                        o  owing?
                      Te Hypercoagulable State                                                                                         A.  T e   ost co    on s  eci  c  actor inhibitor

                      *10.  Which  o   the   o  owing   actors  can  contribute  to                                                    B.  Acquire   inhibitors o  c otting   roteins


                             hy  ercoagu ation?                                                                                        C.  A so known as anti  hos  ho i  i   or anticar  io i  in
                             A.  Vascu ar en  othe ia    a  age                                                                        D.  None o  the above


                             B.  Increase   b oo   f ow
                             C.  Decrease      ate ets                                                                         *18.  A characteristic o   actor VIII inhibitor is which o  the


                             D.  Decrease   titers o  c otting  actors                                                                  o  owing?
                                                                                                                                       A.  T e   ost co    on s  eci  c  actor inhibitor
                      *11.  Antithro  bin   e  ciency can cause a                                                                      B.  Acquire   inhibitors o  c otting   roteins


                             A.    ri  ary hy  ercoagu ab e state                                                                      C.  A so known as anti  hos  ho i  i   or anticar  io i  in
                             B.  secon  ary hy  ercoagu ab e state                                                                     D.  None o  the above




                      *12.  Ora  contrace  tives can cause a                                                                   Anticoagulant T erapy
                             A.    ri  ary hy  ercoagu ab e state


                             B.  secon  ary hy  ercoagu ab e state                                                               19.  War arin is a vita  in                             antagonist.
                                                                                                                                       A.  B
                      *13.  Protein C   e  ciency can cause a                                                                          B.  C


                             A.    ri  ary hy  ercoagu ab e state                                                                      C.  D
                             B.  secon  ary hy  ercoagu ab e state                                                                     D.  K




                        14.  Cancer can cause a
                             A.    ri  ary hy  ercoagu ab e state


                             B.  secon  ary hy  ercoagu ab e state










                                                                                                                               Caste  one D. A case stu  y in coagu ation, Adv Lab, 15(1):51–53, 2006.
                     COMPANION RES OURCES                                                                                      Chaturve  i S, McCrae KR. T e anti  hos  ho i  i   syn  ro  e: sti   an


                                                                                                                                     enig  a, Hematology Am Soc Hematol Educ Program, 2015:53–60,
                     htt  ://the  oint. ww.co  /  urgeon6e
                                                                                                                                     2015.

                     Each stu  ent is encourage   to access an   use the Web-                                                    Cuker A, Siega  D. Monitoring an   reversa  o    irect ora  anticoagu-

                     base   co    anion resources   eve o  e    or this cha  ter.                                                     ants, Hematology Am Soc Hematol Educ Program, 2015:117–124,

                     Here you wi     n   a    itiona   earning too s to increase                                                     2015.

                     your un  erstan  ing o  the conce  ts an   c inica  a     ica-                                             Danese S, et a . T e   rotein C   athway in tissue inf a    ation an
                                                                                                                                     injury:    athogenic  ro e  an    thera  eutic  i     ications,  Blood,
                     tions o  the cha  ter.
                                                                                                                                     115(6):1121–1130, 2010.

                                                                                                                                Fe  erici  AB.  VWF    ro  e  ti  e:  a  use u     arker  in  VWD,  Blood,

                                                                                                                                     108(10):3229, 2006.

                   BIBLIOGRAPHY                                                                                                  Ferro A. Newer anti   ate et agents in acute coronary syn  ro  e, BMJ,

                                                                                                                                     352:h7025, 2016.

                   Bates SM, Ginsberg JS.   reat  ent o    ee  -vein thro  bosis, N Engl                                         Frits  a GA, Marques MB.   o   10   rob e  s in coagu ation, Adv Med

                         Med, 351(3):268–277, 2004.                                                                                  Lab Pro , 16(13):22–29, 2004.
                   Bernar   GR, et a . E  cacy an   sa ety o  reco  binant hu  an activate                                     Frits  a MG. Use o  b oo     ro  ucts an    actor concentrates  or coagu-

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