Page 41 - Review of Medical Microbiology and Immunology ( PDFDrive )
P. 41

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 mebooksfree.com  mebooksfree.com           mebooksfree.com            outside of the colon. The two most important members of the         mebooksfree.com
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                      PART I  Basic Bacteriology
                 30
                    drug users. S. aureus is also present on the skin, but its main
                                                                       colonic flora that cause disease are the anaerobe B. fragilis and
                    site is in the nose. It causes abscesses in the skin and in many
                    other organs.
                                                                       the facultative  E. coli. E. faecalis, a facultative, is also a very
                                                                       important pathogen.
                   •  Oropharynx. The main members of the normal flora of the
                    mouth and throat are the  viridans streptococci, such as  S.
                                                                       isms in the vagina. They keep the pH of the vagina low, which
                    sanguinis and  S. mutans.  Viridans streptococci are the most
                    common cause of subacute endocarditis.
                                                                       inhibits the growth of organisms such as C. albicans, an impor-
                                                                       tant cause of vaginitis.
                   •  Gastrointestinal tract. The stomach contains very few organ-  •  Vagina. Lactobacilli are the predominant normal flora organ-
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 mebooksfree.com  mebooksfree.com           mebooksfree.com          4.  An outbreak of postsurgical wound infections caused by S.         mebooksfree.com
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                                                                     •  Urethra. The outer third of the urethra contains a mixture of
                    isms because of the low pH. The colon contains the  largest
                                                                       bacteria, primarily  S. epidermidis.  The female urethra can
                    number of normal flora and the most diverse species, includ-
                                                                       become colonized with fecal flora such as E. coli, which predis-
                    ing both anaerobic and facultative bacteria.  There are both
                    gram-positive and gram-negative rods and cocci. The members
                                                                       poses to urinary tract infections.
                    of the colonic normal flora are an important cause of disease
                    SELF-ASSESSMENT QUESTIONS
                                                                        aureus has occurred in the hospital. The infection control
                    1.  The colon is the site of the largest number of normal flora
                                                                        team was asked to determine whether the organism could be
                      bacteria. Which one of the following bacteria is found in the
                                                                        carried by one of the operating room personnel. Using your
                      greatest number in the colon?                    (A)  Colon
                                                                        knowledge of normal flora, which one of the following body
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 mebooksfree.com  mebooksfree.com           mebooksfree.com          ANSWERS                                mebooksfree.com                mebooksfree.com
                                                                        sites is the most likely location for this organism?
                      (A)  Bacteroides fragilis
                      (B)  Clostridium perfringens
                      (C)  Enterococcus faecalis
                                                                       (B)  Gingival crevice
                      (D)  Escherichia coli
                                                                       (C)  Mouth
                      (E)  Lactobacillus species
                                                                       (D)  Nose
                    2.  A 76-year-old woman with a prosthetic (artificial) hip comes
                                                                       (E)  Throat
                      to you complaining of fever and pain in that joint. You are
                      concerned about an infection by S. epidermidis. Using your
                      knowledge of normal flora, what is the most likely source of
                      this organism?
                      (A)  Dental plaque
                                                                     2.  (C)
                      (B)  Mouth
                                                                     3.  (C)
                      (C)  Skin
                                                                     4.  (D)
                      (D)  Stomach                                   1.  (A)
                      (E)  Vagina
 mebooksfree.com  mebooksfree.com           mebooksfree.com          COURSE EXAMINATIONS                    mebooksfree.com                mebooksfree.com
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                    3.  Your patient is a 30-year-old woman with a previous history
                                                                     PRACTICE QUESTIONS: USMLE &
                      of rheumatic fever who has had fever for the past 2 weeks.
                      On examination, you find a new heart murmur. You suspect
                      endocarditis and do a blood culture, which grows a viridans
                                                                     Questions on the topics discussed in this chapter can be
                      group streptococcus later identified as  S. sanguinis. Using
                                                                     found in the Basic Bacteriology section of Part XIII:
                      your knowledge of normal flora, what is the most likely
                                                                     USMLE (National Board) Practice Questions starting on
                      source of this organism?
                                                                     page 709. Also see Part XIV: USMLE (National Board)
                      (A)  Duodenum
                                                                     Practice Examination starting on page 751.
                      (B)  Skin
                      (C)  Throat
                      (D)  Urethra
                      (E)  Vagina
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