Page 71 - B.Tech Biotech Curriculum and Syllabus R2017 - REC

Department of BIOTECHNOLOGY, REC

COURSE OUTCOMES:
On completion of the course,Students will be able to
 Develop a vaccine using cell culture
 Diagnose animal diseases using molecular tools
 Analyze the efficiency of different gene transfer methods
 Apply the use of different transgenic animals for different applications
 Pursue higher studies and do specialization in animal biotechnology

TEXT BOOKS
1. Ranga M.M. Animal Biotechnology. Agrobios India Limited, 2002
2. Ramadass P, Meera Rani S. Text Book Of Animal Biotechnology. Akshara Printers, 1997.

REFERENCE
1. Masters J.R.W. Animal Cell Culture: Practical Approach. Oxford University Press.2000

BT17E62 SYSTEMS BIOLOGY L T P C 3
0 0 3

OBJECTIVES:
 To understand overview of Systems Biology
 To provide knowledge onSystems Microbiology and Developmental Systems Biology
 To gain knowledge on Network Biology andapplications of Enzyme Kinetics
 To know different tools of Systems Biology and application.

UNIT I SYSTEMS BIOLOGY FUNDAMENTALS 9
Overview of Ssytems Biology-Overview of Gene Control-Gene Control Mechanisms at Transcription and
Translation Levels-Genetic Switches-The Biochemical, Genetics and the Systems Biology Paradigm

UNIT II SYSTEMS MICROBIOLOGY & DEVELOPMENTAL SYSTEMS BIOLOGY
9
Quorum Sensing - The Language of Bacteria- Programmed Population control by Cell-cell Communication
and Regulated killing-Drosophila melanogaster-Life Cycle-Drosophila melanogaster- Morphogen Gradient-
Establishment of Developmental Precision and Proportions in the Early Drosophila Embryo.

UNIT III ENZYME KINETICS & NOISE IN GENE EXPRESSION 9
Enzyme Kinetics-.MichaelisMenten Kinetics- Binding and Cooperativity- Enzyme Inhibition-Identical
Independent Binding Sites-Sequential Model of Cooperativity-Non-Identical, Interacting Binding Sites-The
Structure and Genetic Map of Lambda phage-Noise and Gene Expression and Gene Regulatory Networks-The
signalling pathway in chemotaxis.

UNIT I IV GENE EXPRESSION NETWORKS 9
Gene Expression Networks-Transcription Networks-Networks in Biology - Network Motifs-Feed Forward
Loops in Biological Systems-Coherent and InCoherent Feed Forward Loops-Kinetics of CFFL-1- Sign
Sensitive Delay-Kinetics of ICFFL-1- Sign Sensitive Accelerator.

UNIT V TOOLS FOR SYSTEMS BIOLOGY 9
Pathway mapping through KEGG, Cytoscape, Virtual Cell, Gene network using R.

TOTAL: 45 PERIODS
COURSE OUTCOMES:
On completion of the course, Students will be able
 To gain knowledge about Systems Biology and Network Biology.
 To provide knowledge on Systems Microbiology and Developmental Systems Biology
 Apply the knowledge in Enzyme Kinetics
Curriculum and Syllabus | B.Tech. Biotechnology | R2017 Page 71