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Immunology  ` Immunology—lymphoId StructureS  Immunology  ` Immunology—lymphoId StructureS            SECTIon II         97




                  Lymphatic drainage associations


                                                           Lymph node cluster  Area of body drained  Associated pathology
                                                                                                Upper respiratory tract infection
                                                           Cervical, supraclavicular  Head and neck  Infectious mononucleosis
                                                                                                Kawasaki disease
                                                                                                Pulmonary TB
                                                           Mediastinal     Trachea and esophagus
                                                                                                Sarcoidosis (bilateral)
                                                                                                1° lung cancer
                                                           Hilar           Lungs                Granulomatous disease
                                                                           Upper limb, breast, skin above  Mastitis
                                                           Axillary
                                                                           umbilicus            Metastasis (especially breast cancer)
                                                                           Liver, stomach, spleen, pancreas,
                                                           Celiac
                                                                           upper duodenum
                                                                                                Mesenteric lymphadenitis
                                                                           Lower duodenum, jejunum, ileum,  Typhoid fever
                                                           Superior mesenteric
                                                                           colon to splenic flexure  Ulcerative colitis
                                                                                                Celiac disease
                                                                           Colon from splenic flexure to
                                                           Inferior mesenteric
                                                                           upper rectum
                                                           Para-aortic     Testes, ovaries, kidneys, uterus  Metastasis
                                                                           Cervix, superior bladder, and
                                                           External iliac
                                                                           body of uterus
                                                                           Lower rectum to anal canal (above
                                                           Internal iliac  pectinate line), bladder, vagina  Sexually transmitted infections
                                                                           (middle third), cervix, prostate  Medial foot/leg cellulitis
                                                                                                (superficial inguinal)
                                                                           Anal canal (below pectinate line),
                                                           Superficial inguinal  skin below umbilicus (except
                                                                           popliteal area), scrotum, vulva
                                Palpable lymph node        Popliteal       Dorsolateral foot, posterior calf  Lateral foot/leg cellulitis
                                Non-palpable lymph node
                                                            Right lymphatic duct drains right side of body above diaphragm into junction of the right
                                                            subclavian and internal jugular vein
                                                            Thoracic duct drains below the diaphragm and left thorax and upper limb into junction of left
                                                            subclavian and internal jugular veins (rupture of thoracic duct can cause chylothorax)









































          FAS1_2019_02-Immunology.indd   97                                                                             11/7/19   3:24 PM
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