Page 162 - First Aid for the USMLE Step 1 2020, Thirtieth edition [MedicalBooksVN.com]_Neat

118 SECTIon II Immunology ` Immunology—Immune reSponSeS Immunology ` Immunology—Immune reSponSeS

Infections in immunodeficiency
pathogen  t cellS  B cellS  granulocyteS  complement
Bacteria Sepsis Encapsulated (Please Some Bacteria Encapsulated
SHINE my SKiS): Produce No species with early
Pseudomonas Serious granules: complement
aeruginosa, Staphylococcus, deficiencies
Streptococcus Burkholderia cepacia, Neisseria with late
pneumoniae, Pseudomonas complement (C5–
Haemophilus aeruginosa, Nocardia, C9) deficiencies
Influenzae type b, Serratia
Neisseria
meningitidis,
Escherichia coli,
Salmonella,
Klebsiella
pneumoniae,
Group B
Streptococcus
Viruses CMV, EBV, JC Enteroviral N/A N/A
virus, VZV, chronic encephalitis,
infection with poliovirus
respiratory/GI viruses (live vaccine
contraindicated)
Fungi/parasites Candida (local), PCP, GI giardiasis (no IgA) Candida (systemic), N/A
Cryptococcus Aspergillus, Mucor
Note: B-cell deficiencies tend to produce recurrent bacterial infections, whereas T-cell deficiencies produce more fungal and
viral infections.

FAS1_2019_02-Immunology.indd 118 11/7/19 3:24 PM