Page 729 - First Aid for the USMLE Step 1 2020, Thirtieth edition [MedicalBooksVN.com]_Neat
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RespiRatoRy  ` RESPIRATORY—PAThOlOgY                     RespiRatoRy  ` RESPIRATORY—PAThOlOgY         seCtioN iii      685




                  Lung abscess           Localized collection of pus within       Lung abscess 2° to aspiration is most often found
                                          parenchyma  A . Caused by aspiration of   in right lung. Location depends on patient’s
                   A
                                          oropharyngeal contents (especially in patients   position during aspiration: RLL if upright,
                                          predisposed to loss of consciousness [eg,   RUL or RML if recumbent.
                                          alcoholics, epileptics]) or bronchial obstruction
                                          (eg, cancer).
                                         Air-fluid levels  B  often seen on CXR;
                                          presence suggests cavitation. Due to
                                          anaerobes (eg, Bacteroides, Fusobacterium,
                   B                      Peptostreptococcus) or S aureus.
                                         Treatment: antibiotics, drainage, or surgery.











                  Pancoast tumor         Also known as superior sulcus tumor. Carcinoma that occurs in the apex of lung  A  may cause
                   A                      Pancoast syndrome by invading/compressing local structures.
                                         Compression of locoregional structures may cause array of findings:
                                             ƒ Recurrent laryngeal nerve Ž hoarseness
                                             ƒ Stellate ganglion Ž Horner syndrome (ipsilateral ptosis, miosis, anhidrosis)
                         1st rib             ƒ Superior vena cava Ž SVC syndrome
                        Mass                 ƒ Brachiocephalic vein Ž brachiocephalic syndrome (unilateral symptoms)
                                             ƒ Brachial plexus Ž sensorimotor deficits
                                             ƒ Phrenic nerve Ž hemidiaphragm paralysis (hemidiaphragm elevation on CXR)



                  Superior vena cava     An obstruction of the SVC that impairs blood   B
                  syndrome                drainage from the head (“facial plethora”;
                                          note blanching after fingertip pressure in  A ),
                   A                                                                             SVC
                                          neck (jugular venous distention), and upper
                                          extremities (edema). Commonly caused by                    Ao
                                          malignancy (eg, mediastinal mass, Pancoast              clot
                                          tumor) and thrombosis from indwelling
                                          catheters  B . Medical emergency. Can raise                      LV
                                          intracranial pressure (if obstruction is severe)           RA
                                          Ž headaches, dizziness,  risk of aneurysm/
                                          rupture of intracranial arteries.



























          FAS1_2019_16-Respiratory.indd   685                                                                           11/8/19   7:34 AM
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