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INDEX                                                                                        INDEX                     779




                  Leukocoria, 538            Linear viruses, 163         cystic fibrosis, 60      LPS endotoxin, 124, 131, 133, 145
                  Leukocyte adhesion deficiency, 117,   Lines of Zahn, 672  hepatosteatosis, 72   LTB  (Leukotriene B4), 406, 485
                                                                                                     4
                         215                 Lineweaver-Burk plot, 230   hereditary, 394          Lumbar puncture, 507, 521
                  Leukocyte alkaline phosphatase   Linezolid, 193        ischemia in, 210         Lumbosacral radiculopathy, 455
                         (LAP), 406            highly resistant organisms, 198  metastases to, 223  Lumbrical muscles, 450
                  Leukocyte esterase, 181, 600  protein synthesis inhibition, 191  serum markers, 390  Klumpke palsy and, 448
                  Leukocytes                 Lingula (lung), 663         target cells in, 415       median and ulnar nerves, 447
                    extravasation, 214, 215  Linkage disequilibrium, 57  Wilson disease and, 395  Lumefantrine, 200
                    leukemias, 432           Liothyronine (T3), 354     Liver failure             Lunate bone, 449
                    in urine, 181, 594, 600  Lipase                      Budd-Chiari syndrome and, 392  Lung abscesses, 685
                  Leukocytoclastic vasculitis, 173  pancreatic secretions, 373  movement disorder in, 519  Lung and chest wall expansion, 665
                  Leukocytosis, 213            in pancreatitis, 397     Liver fluke               Lung cancer
                    diabetic ketoacidosis, 347  Lipid-lowering agents    hyperbilirubinemia with, 393  asbestosis and, 677
                    nosocomial infections, 185  mechanism and adverse effects,   as oncogenic microbe, 226  carcinogens causing, 225
                  Leukodystrophies, 494, 524       320–321              Liver function tests        cisplatin/carboplatin for, 442
                  Leukoerythroblastic reaction, 424  Lipid metabolism    cholestatic pattern of, 395  erlotinib for, 442
                  Leukopenias, 424             fatty acids, 73           serum markers for, 390     hypercalcemia and, 228
                    cytarabine, 440          Lipids                     Liver markers               incidence/mortality in, 222
                    ganciclovir, 202           key enzymes in, 93        in alcohol use, 570        metastases to, 223
                    trimethoprim, 194          transport of, 92–93      Liver tumors, 392           non–small cell, 684
                  Leukoplakia, 479           Lipodystrophy              Living wills, 266           oncogenes and, 224
                  Leukotrienes                 protease inhibitors, 203  Loa loa, 159               paraneoplastic syndromes and,
                    basophils and, 408         tesamorelin for, 328     Loading dose, 231               228
                    cortisol effects, 336    Lipofuscin, 211            Lobar pneumonia             presentation and complications,
                  Levator veli palatini muscle, 620  Lipoic acid, 76     natural history of, 683        684
                  Levetiracetam, 544         Lipolysis                   organisms and characteristics, 683  small cell, 684
                  Levodopa, 548, 549           cortisol and, 336         physical findings with, 680  topotecan for, 442
                  Levofloxacin                 insulin and, 334         Lobular carcinoma (breast), 650  Lung diseases
                    fluoroquinolones, 195      sympathetic receptors and, 238  Local anesthetics, 550  obstructive, 674–675
                    Pseudomonas aeruginosa, 143  thyroid hormone and, 331  Localized amyloidosis, 212  restrictive, 675
                  Levomilnacipran, 575       Lipomas, 220               Locked-in syndrome        Lungs
                  Levonorgestrel, 657        Lipophilic drug             osmotic demyelination syndrome,   anatomical relationships, 663
                  Levothyroxine, 354           drug metabolism of, 232        524                   blood flow regulation, 297
                  Lewy bodies, 520, 521      Lipoprotein lipase, 93      stroke, 515                development of, 660
                    dementia, 521            Lipoproteins, 93           Locus ceruleus, 495         physical findings, 680
                  Leydig cells                 functions of, 94         Locus heterogeneity, 57     sclerosis of, 473
                    cryptorchidism, 651      Liposarcomas, 220          Löffler endocarditis, 308   transfusion-related injury, 114
                    endocrine function, 628, 638  Lipoteichoic acid     Löffler medium, 126       Lung volumes, 664
                    genital embryology, 622    cytoplasmic membrane, 124  Corynebacterium diphtheriae, 139  Lung zones, 669
                    tumors of, 653           Liquefactive necrosis, 209  Lomustine, 441           Lupus
                  LFA-1 antigens, 215        Liraglutide, 353           Lone Star tick (disease vector), 149  autoimmune hemolytic anemia
                  Libido                     Lisch nodules, 525         Long-chain fatty acid (LCFA)    and, 423
                    in geriatric patients, 270  Lisdexamfetamine, 572    metabolism of, 89          azathioprine for, 440
                    testosterone and, 636    Lisinopril, 610            Long QT syndrome            drug-induced, 115
                  Libman-Sacks endocarditis, 470  Lispro, 352            congenital, 294            isoniazid, 197
                  Lice                       Lissencephaly, 491          ranolazine, 319            lymphopenia, 424
                    disease vectors, 149     Listeria monocytogenes      sudden cardiac death, 304  marantic endocarditis in, 311
                    head/scalp, 161            β-hemolysis, 135         Long thoracic nerve         microangiopathic hemolytic
                    treatment, 200             neonates, 182             arm abduction, 446             anemia,, 423
                  Lichen planus, 173, 475, 482  penicillins for, 188     neurovascular pairing, 455  nephritis, 470
                  Lichen sclerosus, 644        transmission of, 139     Loop diuretics, 608         neutropenia, 424
                  Lichen simplex chronicus, 644  Listeria spp            for heart failure, 309   Lupus anticoagulant, 115
                  Liddle syndrome, 586         facultative intracellular organisms,   toxicity of, 251  Lupus-like syndrome
                    markers in, 591                127                  Loop of Henle, 608          α-methyldopa, 243
                  Lidocaine, 322, 550          intracellular organism, 127  Bartter syndrome and, 586  hydralazine, 318
                  Life support               Lithium                     ethacrynic acid effect on, 608  procainamide, 322
                    withdrawal, 269            diabetes insipidus and, 249, 338  “loose associations,” 559  Lurasidone, 573
                  Li-Fraumeni syndrome         hypothyroidism, 341      Looser zones (osteomalacia), 463  Luteal phase of menstrual cycle, 632
                    osteosarcomas, 465         mechanism and use, 574   Loperamide, 400, 551      Luteinizing hormone (LH)
                    tumor suppressor genes in, 46, 224  prenatal exposure, 298, 300  Lopinavir      clomiphene effect, 656
                  Ligaments                    teratogenicity, 614       HIV therapy, 203           contraception, 657
                    female reproductive anatomy, 625  therapeutic index of, 234  Loratadine, 686    estrogen/progesterone, 630
                    gastrointestinal anatomy, 361  thyroid functions with, 249  Lorazepam           hCG and, 617
                  Ligamentum arteriosum, 282   toxicity of, 569          alcohol withdrawal, 572    ovulation, 631
                  Ligamentum teres hepatis, 282, 361  Live attenuated vaccines, 111  Losartan, 610  PCOS, 645
                  Ligamentum venosum, 282    Liver                      Low birth weight, 635       premature ovarian failure, 636
                  Ligand receptors, 208        blood supply and innervation of, 364  Löwenstein-Jensen agar/medium, 126  secretion of, 327
                  Lightheadedness, 534         in gastrointestinal anatomy, 361  Lower esophageal sphincter (LES)  sex development disorders, 639
                  Likelihood ratio (LR), 257   lipid transport and, 92   achalasia and, 376         signaling pathways of, 337
                  Limbic system, 499           tissue architecture, 367  in Barrett esophagus, 377  spermatogenesis, 628
                  Limited scleroderma (CREST   Liver/biliary disease     nitric oxide and, 371      testosterone, 658
                         syndrome), 115, 473   acanthocytes in, 414     Lower extremity nerves, 452–453  Lyme disease
                  Linagliptin, 353             alcoholic, 391           Lower left quadrant (LLQ) pain, 383  animal transmission, 149
                  Lindane, 200                 anemia, 420              Lower motor neuron (LMN) lesions,   AV block in, 295
                  Linea alba, 369              autoimmune, 389, 392, 395      530, 531              Borrelia burgdorferi, 146
                  Linear ulcers, 377           cirrhosis, 71, 80, 389    facial nerve, 532          ceftriaxone, 189







          FAS1_2019_21_Index_749-806.indd   779                                                                        11/21/19   12:27 PM
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