Page 354 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003
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A. Olfactory pathway and olfactory sensor specificity
1 Nasal cavity
2 Olfactory pathway
Olfactory bulb
Olfactory bulb
Fila olfactoria
Olfactory region
Granular cell
Mitral cell
Reciprocal
Air synapses (+/–)
Bristle cells Sense of Smell
Periglomerular
cell
3 Sensor specificity (example)
AP/Stimulus
ortho meta para
CH 3 CH 3 Plate 12.16
Glomerulus 1
CH 3 CH 3 CH 3 CH 3
Glomerulus 2
Length of side chain CH 3 CH 2 CH 3 CH 3 CH 2 CH 3 CH 3 CH 2 CH 3 olfactoria
Fila
Olfactory
CH 3
CH 3
sensor cells
CH 2 CH 2 CH 3 CH 2 CH 2 CH 3 CH 3 CH 2 CH 2 CH 3
Cilia
(After K. Katoh et al.) Mucus (After K. Mori et al.)
B. Transduction of olfactory stimuli C. Adaptation of smell and taste
Mucous layer Odorant Cation Gustatory stimulus: 2mol/L NaCl
Olfactory stimulus: 0.02mol/LH 2 S
channel
Receptor 100 Smell
Cell membrane GTP G s -protein Intensity of perception (%) 50
GDP Taste
Adenylate
cyclase
ICF
ATP Na + 0 1 2 3 4 5
cAMP Ca 2+ Time (min) 341
(After Engel and Ekman et al.)
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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