Page 367 - ACCCN's Critical Care Nursing
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344  P R I N C I P L E S   A N D   P R A C T I C E   O F   C R I T I C A L   C A R E

         PAO 2  and PaO 2 , the larger the degree of intrapulmonary   administration  of  nebulised  saline  (isotonic  or  hyper-
                                                                                                   58
         shunting. 54                                         tonic)  can  assist  in  producing  a  sample.   There  is  no
                                                              evidence  to  support  this  for  mechanically  ventilated
         The PaO 2 /FiO 2  ratio was introduced as a simpler way of
         estimating pulmonary shunting, even though it does not   patients,  but  anecdotally  nebulised  normal  saline  may
         formally  measure  alveolar  partial  pressure.  It  remains   assist in moistening the airways and thinning secretions
         widely used to define ALI or ARDS. A PaO 2 /FiO 2  ratio of   to  facilitate  sputum  production.  Physiotherapy  is  often
                                                                                                  59,60
         <300 indicates ALI and a ratio of <200 indicates ARDS.   useful  in  producing  a  sputum  sample,    as  manual
         For example, for a patient receiving an FiO 2  of 0.65 with   hyperinflation and head downtilt during the physiother-
                                                                                                      61,62
         a PaO 2  of 90 mmHg (12 kPa), their PaO 2 /FiO 2  ratio is   apy session has increased sputum production.
         138.5, indicating an ARDS state. 55                  Instilling normal saline in an endotracheal tube (ETT) to
                                                              facilitate clearance of tenacious sputum and obtain a tra-
         BLOOD TESTS                                          cheal aspirate remains a controversial issue. There is no
         Investigation of haematology and biochemistry values for   evidence  that  instillation  facilitates  secretion  clearance,
         a patient with respiratory dysfunction can aid their overall   while there is some evidence that it is more uncomfort-
         treatment. Full blood count (FBC), including a leukocyte   able for a patient and increases the risk of contamination
         differential count, can track a patient’s white cell count   of the lower airway with bacteria. The practice is therefore
                                                                               63
         (WCC)  if  they  have  a  confirmed  or  suspected  infective   not recommended.
         process. When infections are severe, the FBC will show a   Nasopharyngeal  aspirates  (NPA)  or  nasopharyngeal
         dramatic  rise  in  the  number  of  immature  neutrophils.   swabs (NPS) may be necessary to diagnose viral respira-
         Blood cultures can also be drawn to assist in diagnosis   tory infections. The NPA is collected by inserting a fine
         of bacterial or yeast infections and isolation of the caus-  sterile suction catheter (8 or 10 F), attached to a sputum
         ative  organism.  Viral  studies  may  be  conducted  to  aid   trap and suction, through the nare and back to the naso-
         diagnosis  for  respiratory  infections  of  unknown  origin.   pharynx. Suction is applied while withdrawing the cath-
         If the patient is suspected of having a pulmonary embo-  eter  slowly  using  a  rotating  motion.  Flush  the  catheter
         lism,  a  D-dimer  test  can  determine  the  presence  of  a   through to the sputum trap with sterile normal saline or
         thrombus.  Urea  and  electrolytes  will  also  be  routinely   transport  medium  if  available.  A  NPS  is  collected  by
         measured to monitor a patient’s renal function and acid–  inserting  a  specially  designed  swab  to  the  back  of  the
         base status. 56                                      nasopharynx and rotating for 5–10 seconds, withdrawing
                                                              slowly then placing the swab into the plastic vial contain-
                                                              ing transport medium. 64
            Practice tip
                                                              DIAGNOSTIC PROCEDURES
            Monitoring lactate levels is important as this reflects the effec-  Assessment and monitoring of the respiratory status of a
            tiveness and efficiency of resuscitative therapies. A persistently   critically ill patient commonly relies on diagnostic tests,
            elevated lactate level is associated with higher morbidity and   including  various  medical  imaging  tests  and  bronchos-
            poorer patient outcomes.
                                                              copy. Data generated through diagnostic procedures are
                                                              used to determine the cause of illness, the severity of the
                                                              illness episode, relevant comorbidities and the patient’s
         SPUTUM, TRACHEAL ASPIRATES AND                       response to treatment.
         NASOPHARYNGEAL ASPIRATES
         Colour,  consistency  and  volume  of  sputum  provides   MEDICAL IMAGING
         useful information in determining changes in a patient’s   A range of imaging techniques may be available for sup-
         respiratory status and progress. Regular cultures of tracheal   porting  care  of  a  critically  ill  patient  with  a  respiratory
         sputum facilitates tracking of colonisation by opportunis-  dysfunction,  depending  on  the  level  of  broader  health
         tic organisms, or the identification of the cause of an acute   service  resources  available.  This  sub-section  describes
         chest infection or sepsis. Many ICUs have routine surveil-  X-ray,  ultrasound,  computerised  tomography,  magnetic
         lance  monitoring  (weekly  or  twice-weekly)  of  tracheal   resonance  imaging  and  ventilation/perfusion  scan
         aspirates  in  long-term  mechanically-ventilated  patients.   techniques.
         In spontaneously breathing patients, sputum specimens
         can be provided into a sterile specimen receptacle. These   Chest X-ray
         specimens  are  best  collected  early  in  the  morning  and
         assisting the patient to clean their teeth prior to sample   Chest X-ray (CXR) is a common diagnostic tool used for
         collection prevents secondary contamination. In an intu-  respiratory  examination  of  critically  ill  patients.  Chest
         bated patient, a sputum sample is collected by suctioning   radiography  allows  basic  information  regarding  abnor-
         the  artificial  airway  using  a  sputum  trap  between  the   malities in the chest to be obtained relatively quickly. The
         suction  catheter  and  suction  tubing.  Maintain  a  sterile   image provides information about lung fields and other
         technique so that the specimen is not contaminated. 57  thoracic  structures  as  well  as  the  placement  of  various
                                                              invasive lines and tubes. 65,66  In the critically ill ventilated
         If  obtaining  an  adequate  sputum  specimen  in  non-   patient, serial chest X-rays also enable sequential assess-
         intubated  patients  is  difficult,  there  is  evidence  that   ment of lung status in relation to therapy. 66
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