Page 2106 - Hematology_ Basic Principles and Practice ( PDFDrive )

Chapter 124 Megakaryocyte and Platelet Structure 1869

24. Patel-Hett S, Richardson JL, Schulze H, et al: Visualization of micro- 32. Bender M, Thon JN, Ehrlicher AJ, et al: Microtubule sliding drives
tubule growth in living platelets reveals a dynamic marginal band with proplatelet elongation and is dependent on cytoplasmic dynein. Blood
multiple microtubules. Blood 111:4605, 2008. 125:860, 2015.
25. Freson K, De Vos R, Wittevrognel C, et al: The β1-tubulin Q43P 33. Begonja A, Hoffmeister KM, Hartwig JH, et al: FlnA-null megakaryo-
functional polymorphism reduces the risk of cardiovascular disease in cytes prematurely release large and fragile platelets that circulate poorly.
men by modulating platelet function and structure. Blood 106:2356, Blood 118:2285, 2011.
2005. 34. Bender M, Eckly A, Hartwig JH: ADF/n-cofilin-dependent actin
26. Nakamura F, Stossel TP, Hartwig JH: The filamins: organizers of cell turnover determines platelet formation and sizing. Blood 116:1767,
structure and function. Cell Adh Migr 5:160, 2011. 2010.
27. Nakamura F, Pudas R, Heikkinen O, et al: The structure of the GP1b- 35. Bender M, Stritt S, Nurden P, et al: Megakaryocyte-specific Profilin1-
filamin A complex. Blood 107:1925, 2005. deficiency alters microtubule stability and causes a Wiskott-Aldrich
28. Eckly A, Heijnen H, Pertuy F, et al: Biogenesis of the demarcation syndrome-like platelet defect. Nat Commun 5:4746, 2014.
membrane system (DMS) in megakaryocytes. Blood 123:921, 2014. 36. Pleines I, Dütting S, Cherpokova D, et al: Defective tubulin organiza-
29. Wandall HH, Rumjantseva V, Sørensen AL, et al: The origin and func- tion and proplatelet formation in murine megakaryocytes lacking Rac1
tion of platelet glycosyltransferases. Blood 120:626, 2012. and Cdc42. Blood 122:3178, 2013.
30. Chen Y, Aardema J, Kale S, et al: Loss of the F-BAR protein CIP4 37. Pleines I, Hagedorn I, Gupta S: Megakaryocyte-specific RhoA deficiency
reduces platelet production by impairing membrane-cytoskeleton causes macrothrombocytopenia and defective platelet activation in
remodeling. Blood 22:1695, 2013. hemostasis and thrombosis. Blood 119:1054, 2012.
31. Bender M, Giannini S, Grozovsky R, et al: Dynamin 2-dependent 38. Diagouraga B, Grichine A, Fertin A, et al: Motor-driven marginal band
endocytosis is required for normal megakaryocyte development in mice. coiling promotes cell shape change during platelet activation. J Cell Biol
Blood 125:1014, 2015. 204:177, 2014.