Page 853 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPtEr 59 Large-Vessel Vasculitides 824.e1

MUL t IPLE CHOICE QUES t IONS

1. A 27-year old female presents with a 6-weeks history of C. Subclavian artery
intermittent fever, arthralgias and weight loss. She was admitted D. Renal capillaries
after she fainted in the emergency room. On physical examina- E. Arteries in the skin
tion she has no palpable peripheral pulse in her left upper 3. Extravascular GCA may result in the following laboratory
extremity, and Takayasu arteritis (TA) is added as a differential abnormalities. Identify the incorrect answer:
diagnosis. A. Elevated C-reactive protein
Which of the following statements is true: B. Autoantibodies to nuclear antigens
A. She should be scheduled for temporal artery biopsy, to C. Thrombocytosis
rule out giant cell arteritis. D. Elevated serum amyloid A
B. Laboratory tests, e.g. sedimentation rate will be of no use, E. Elevated alkaline phosphatase
as they can be non-specifically abnormal.
C. A pregnancy test should be performed.
D. A detailed physical examination will not be helpful.
E. If a diagnosis of TA is made, it will be a self-limited disease.
2. Giant cell arteritis and Takayasu arteritis have a stringent
tissue tropism. Which of the following vascular beds can be
involved? Identify all correct answers:
A. Aortic arch
B. Carotid artery