Page 1001 - Clinical Immunology_ Principles and Practice ( PDFDrive )

966 Part seven Organ-Specific Inflammatory Disease

8. Balasubramanyam A, Nalini R, Hampe CS, et al. Syndromes of 24. Couper JJ, Beresford S, Hirte C, et al. Weight gain in early life predicts
ketosis-prone diabetes mellitus. Endocr Rev 2008;29:292–302. risk of islet autoimmunity in children with a first degree relative with
9. Imagawa A, Hanafusa T, Miyagawa J, et al. A novel subtype of type 1 type 1 diabetes. Diabetes Care 2009;32:94–9.
diabetes mellitus characterized by a rapid onset and an absence of 25. Penno MAS, Couper JJ, Craig ME, et al. Environmental determinants of
diabetes-related antibodies. Osaka IDDM Study Group. N Engl J Med islet autoimmunity (ENDIA): a pregnancy to early life cohort study in
2000;342:301–7. children at-risk of type 1 diabetes. BMC Pediatr 2013;13:124.
10. Imagawa A, Hanafusa T. Pathogenesis of fulminant type 1 diabetes. Rev 26. Knip M, Siljander H. The role of the intestinal microbiota in type 1
Diabet Stud 2006;3:169–77. diabetes mellitus. Nat Rev Endocrinol 2016;12:154–67.
11. Harrison L, Honeyman M, DeAizpurua H, et al. Inverse relationship 27. Thorburn AN, Macia L, Mackay CR. Diet, metabolites, and “Western
between humoral and cellular immunity to glutamic acid decarboxylase lifestyle” inflammatory diseases. Immunity 2014;40:833–42.
in humans at-risk for insulin-dependent diabetes. Lancet 28. Kondrashova A, Reunanen A, Romanov A, et al. A six-fold gradient in the
1993;341:1365–9. incidence of type 1 diabetes at the eastern border of Finland. Ann Med
12. Gale EAM. The rise of childhood type 1 diabetes in the 20th century. 2005;37:67–72.
Diabetes 2002;51:3353–61. 29. Kondrashova A, Seiskari T, Ilonen J, et al. The ‘hygiene hypothesis’ and
13. Fourlanos S, Varney MD, Tait BD, et al. The rising incidence of type 1 the sharp gradient in the incidence of autoimmune and allergic diseases
diabetes is accounted for by cases with lower risk human leukocyte between Russian Karelia and Finland. APMIS 2013;121:478–93.
antigen genotypes. Diabetes Care 2008;31:1546–9. 30. Honeyman M. How robust is the evidence of viruses in the induction of
14. Tait BD, Colman PG, Morahan G, et al. HLA genes associated with type 1 diabetes? Curr Opin Immunol 2005;17:616–23.
autoimmunity and progression to disease in type 1 diabetes. Tissue 31. Roivainen M, Klingel K. Virus infections and type 1 diabetes risk. Curr
Antigens 2003;61:146–53. Diab Rep 2010;10:350–6.
15. Fourlanos S, Narendran P, Byrnes GB, et al. Insulin resistance is a 32. Menser MA, Forrest JM, Honeyman MC, et al. Letter: diabetes, HL-A
risk factor for progression to type 1 diabetes. Diabetologia antigens, and congenital rubella. Lancet 1974;2:1508–9.
2004;47:1661–7. 33. Honeyman MC, Coulson BS, Stone NL, et al. Association between
16. Eisenbarth GS. Type I diabetes mellitus. A chronic autoimmune disease. rotavirus infection and pancreatic islet autoimmunity in children at-risk
N Engl J Med 1986;314:1360–8. for type 1 diabetes. Diabetes 2000;49:1319–24.
17. Willcox A, Richardson SJ, Bone AJ, et al. Analysis of islet inflammation in 34. Honeyman MC, Laine D, Londrigan S, et al. Rotavirus infection induces
human type 1 diabetes. Clin Exp Immunol 2009;155:173–81. transient pancreatic involution and hyperglycemia in weanling mice.
18. Barrett JC, Clayton DG, Concannon P, et al. Genome-wide association PLoS ONE 2014;9:e106560.
study and meta-analysis find that over 40 loci affect risk of type 1 35. Harrison LC, Wentworth JM, Zhang Y, et al. Antigen-based vaccination
diabetes. Nat Genet 2009;41:703–7. and prevention of type 1 diabetes. Curr Diab Rep 2013;13:616–23.
19. Pociot F, Akolkar B, Concannon P, et al. Genetics of type 1 diabetes: 36. Harrison LC, Wentworth JM. Prevention of autoimmune disease: the type
What’s next? Diabetes 2010;59:1561–71. 1 diabetes paradigm. In: Rose N, Mackay I, editors. The autoimmune
20. Pugliese A, Zeller M, Fernandez A Jr, et al. The insulin gene is transcribed diseases. 5th ed. London, UK: Elsevier Ltd.; 2014. p. 1191–203.
in the human thymus and transcription levels correlated with allelic 37. Staeva TP, Chatenoud L, Insel R, et al. Recent lessons learned from
variation at the INS VNTR-IDDM2 susceptibility locus for type 1 prevention and recent-onset type 1 diabetes immunotherapy trials.
diabetes. Nat Genet 1997;15:293–7. Diabetes 2013;62:9–17.
21. Bennett ST, Lucassen AM, Gough SC, et al. Susceptibility to human type 38. Skyler JS, Krischer JP, Wolfsdorf J, et al. Effects of oral insulin in relatives
1 diabetes at IDDM2 is determined by tandem repeat variation at the of patients with type 1 diabetes: the Diabetes Prevention Trial–Type 1.
insulin gene minisatellite locus. Nat Genet 1995;9:284–92. Diabetes Care 2005;28:1068–76.
22. Atkinson MA, Bluestone JA, Eisenbarth GS, et al. How does type 1 39. Fourlanos S, Perry C, Gellert SA, et al. Evidence that nasal insulin induces
diabetes develop?: the notion of homicide or beta-cell suicide revisited. immune tolerance to insulin in adults with autoimmune diabetes.
Diabetes 2011;60:1370–9. Diabetes 2011;60:1237–45.
23. Eizirik DL, Sammeth M, Bouckenooghe T, et al. The human pancreatic 40. Nanto-Salonen K, Kupila A, Simell S, et al. Nasal insulin to prevent type 1
islet transcriptome: expression of candidate genes for type 1 diabetes and diabetes in children with HLA genotypes and autoantibodies conferring
the impact of pro-Inflammatory cytokines. PLoS Genet 2012;8: increased risk of disease: a double-blind, randomized controlled trial.
e1002552. Lancet 2008;372:1746–55.