Page 875 - Textbook of Pathology, 6th Edition
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unremitting muscular weakness. Six major forms of muscular childhood or in early adulthood. Family history of 859
dystrophies are described: Duchenne’s, Becker’s, myotonic, neuromuscular disease is elicited in many cases.
facio-scapulohumeral, limb-girdle and oculopharyngeal type. Each
type of muscular dystrophy is a distinct entity having MORPHOLOGIC FEATURES. Common to all forms of
differences in inheritance pattern, age at onset, clinical muscular dystrophies are muscle fibre necrosis,
features, other organ system involvements and clinical regenerative activity, replacement by interstitial fibrosis
course. These differences are summarised in Table 28.5. and adipose tissue (Fig. 28.30).
However, in general, muscular dystrophies manifest in
q CHAPTER 28
The Musculoskeletal System
