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328    Chapter 11


                                            airway resistance has been changed. A decrease in total C  is the only explanation for
                                                                                          LT
                                            the increase in PIP, which is supported by the increase in peak P ALV  at end-inspiration.
                                            The same peak flow, flow pattern, and volume (Area 1 5 Area 2) are being used for
                                            volume delivery in each example. Total C  can be estimated by observing the infor-
                                                                              LT
                                            mation provided in the graphic comparison and, in this example, it has decreased by
                                            half. The calculated V  under the flow curve is 1 L or 1000 mL (1 L/sec 3 1 sec),
                                                              T
                                            and total C  is 50 mL/cm H O (C  5 1000 mL/20 cm H O) for the first example,
                                                                    2
                                                     LT
                                                                         LT
                                                                                             2
                                            versus 25 mL/cm H O (1000 mL/40 cm H O) in the second example.
                                                            2
                                                                                2
                      EFFECTS OF DESCENDING RAMP FLOW WAVEFORM
                      DURING VOLUME-CONTROLLED VENTILATION


                                            Time- and Flow-Limited Ventilation


                                            Figure 11-13 demonstrates the changes that occur when the flow pattern on a ven-
                                            tilator is adjusted from a constant to a descending ramp flow waveform (DRFW)
                                            during time-limited ventilation (first example) compared to flow-limited ventilation



                                                 Time-Limited Ventilation (Area a = Area b)
                                         80
                                       V (L/min)      a    b               Flow-Limited Ventilation (Area a = Area b)

                                                                                    a

                                                                                         b
                                                      1        2       3        4       5        6        7







                                       P (cm H 2 O)  280




                                                                                          TA
                                         40               PIP & Initial P TA  Same Initial Peak P  for the Same Initial Flow
                                                               P TA                      P TA
                                                                  Peak P ALV  No                  PIP = Peak P ALV
                                                                  End-Flow No
                                                                  P TA
                                                                                                                  © Cengage Learning 2014

                                         22
                                                      1        2       3        4       5        6        7
                                                                          Time (sec)
                                            Figure 11-13  Changes of dynamic pressure waveforms created by descending ramp flow 
                                            during time-limited and flow-limited ventilation.






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