Page 379 - Clinical Application of Mechanical Ventilation
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Ventilator Waveform Analysis  345


                                             in the V  delivered. Compared to example A, less volume is delivered as shown by
                                                    T
                            During pressure-  the area under the second inspiratory flow waveform in example B. Peak flow is
                          controlled ventilation, a reduc-
                                             maintained, but the slope or descent in flow rate from peak level is greater. Thus, the
                          tion in C LT  will reduce the V T.
                                             average flow and V  are reduced (V  5 average Flow 3 T ). Letter b shows that T  is
                                                                                                                 E
                                                                           T
                                                                                             I
                                                             T
                                             reduced since less volume is expired. The peak expiratory flow rate is about the same
                                             since the resistance to flow is the same, and the driving pressure for expiratory flow,
                                             the PC level set, and end-inspiratory lung pressure, was held relatively constant.
                                             During pressure-controlled ventilation, the pressure is held relatively constant while
                                             the flow and V  delivered are altered by changing lung/airway characteristics.
                                                          T
                        USING WAVEFORMS FOR PATIENT-VENTILATOR
                        SYSTEM ASSESSMENT



                                             Positive pressure in the lungs is not natural. Too much volume under pressure can
                            Patient-ventilator dys-  cause barotraumas or volutrauma. Too little volume or not enough positive end-
                          synchrony increases the work
                          of breathing and prolongs   expiratory  pressure  (PEEP)  to  keep  alveoli  from  collapsing  (derecruitment)  and
                          weaning from mechanical   then reopening (recruitment) during tidal ventilation can cause lung injuries. Too
                          ventilation.
                                             little respiratory muscle use (disuse atrophy) leads to respiratory muscle weakness,
                                             and excessive work of breathing (WOB) leads to respiratory muscle weakness or
                                             fatigue. Either way, weaning from mechanical ventilation is delayed.
                                               No research to date suggests that patients triggering all the volume- or pressure-
                                             controlled breaths in synchrony with the ventilator will develop respiratory muscle
                                             weakness  from  either  too  little  or  too  much WOB.  Conversely,  volumes  of  re-
                                             search suggest that dyssynchrony during ventilator management may impose ex-
                                             cessive WOB  and  prolong  mechanical  ventilation  (Dick  et  al.,  1996).  Research
                                             also suggests lack of assisted ventilation (patient-triggered breaths) from prolonged
                                             paralysis or sedation as a reason for prolonged mechanical ventilation. The best
                                             oxygenation and ventilation should be derived at the lowest volume and least lung
                                             pressure if patients are breathing in synchrony with the ventilator, which obviates
                                             excess WOB and mitigates the potential for excessive lung pressures. Auto-PEEP
                                             can be easily observed and corrected using graphics, which reduces the potential
                                             for volume trauma. Also, patient-ventilator synchrony can be easily verified and
                                             controlled through waveform analysis.


                                             Patient-Ventilator Dyssynchrony


                                             Dyssynchrony during mechanical ventilation increases the WOB, oxygen consump-
                            Dyssynchrony during me-  tion, minute ventilation, and myocardial work. Dyssynchrony can occur with the
                          chanical ventilation increases
                          the WOB, oxygen consump-  assisted (patient-triggered) or controlled (time-triggered) breaths. The first pressure
                          tion, minute ventilation, and   waveform in Figure 11-27 depicts a detailed analysis of an assist (patient-triggered)
                          myocardial work.
                                             breath.  Both  pressure-time  waveforms  depict  the  step  ascending  ramp  pattern.
                                             Thus, a constant (square) flow pattern must have been set to produce these pressure
                                             waveforms. The 22 cm H O value below baseline (zero) represents the sensitivity
                                                                    2
                                             threshold level setting. In the first waveform, the patient’s effort to trigger the breath






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