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284     PART 3: Cardiovascular Disorders


                 causes should be identified and corrected (Table 36-7). 25-27  The     TABLE 36-7    Management of Ventricular Tachycardia due to Reversible Causes
                 serum potassium should be maintained  ≥4.0 mM/L and the serum
                 magnesium should be maintained >0.7 mM/L. β-Blockers should be   Cause              Management
                 prescribed unless contraindicated (Table 36-4). Management of isch-  Acute ischemia/myocardial infarction  Amiodarone and/or β-blockers,
                 emic heart disease, left ventricular dysfunction and/or hypertension                revascularization
                 must be optimized. If ongoing ischemia/cardiogenic shock is present
                 despite medical therapy, the patient should be considered for urgent   Congestive heart failure  Optimize therapy of CHF,
                 coronary artery evaluation and possible revascularization.                            ACE inhibitors,
                 Nonsustained V :  β-Blockers should be prescribed unless contrain-                    β-blockers,
                            T
                 dicated and doses should be titrated to suppress nonsustained V
                                                                    t
                 (Table 36-4). 17,25,28,29  If frequent, hemodynamically significant nonsus-           consider ICD
                 tained V  persists, amiodarone may be initiated for suppression. 17,25-27,30    Electrolyte abnormalities (usually torsade de    MgSO  1-4 g IV, KC1, atrial overdrive
                                                                                                        4
                       t
                 Patients with mild to moderate left ventricular dysfunction (left   pointes V )     pacing
                                                                             t
                 ventricular ejection fraction [LVEF]  >0.30) may be considered for   Drug toxicity/long Qt (torsade de pointes V )  MgSO  1-4 g IV, atrial overdrive pacing
                                                                                  ˙
                 a risk stratification electrophysiology study to determine the risk of        t     (80-100 bpm), discontinue
                                                                                                        4
                 sudden cardiac death. 16,30  Patients with severe left ventricular dysfunc-         class I/III drugs
                 tion in the setting of ischemic heart disease (LVEF ≤ 0.30) or dilated
                 cardiomyopathy should be considered for an implantable cardioverter   Drug toxicity (incessant monomorphic V,    Sodium bicarbonate (50-200 meq IV),
                                                                                              t
                 defibrillator (ICD) for prophylaxis of sudden cardiac death. 21,31,32  eg, flecainide/propafenone/tricyclic antidepressants) lidocaine (0.5-0.75 mg/kg)
                 Monomorphic Ventricular Tachycardia:   The acute management algorithm   Catecholamine sensitive V t  β-Blockers
                 for sustained monomorphic V  is shown in Figure 36-3. This algo rithm is   ACE, angiotensin converting enzyme; CHF, congestive heart failure; ICD, implantable cardioverter defibrillator;
                                      t
                 based  on  the  recommendations  of  the  American  Heart  Association. 26,27    V , ventricular tachycardia.
                                                                        t
                                                         Sustained Monomorphic Ventricular
                                                                 Tachycardia


                                            Synchronized    Yes          Hemodynamic Compromise?
                                            Cardioversion              (Altered mental status, hypotension,
                                             120–200 J a                angina, CHF, or other evidence of
                                                                          impaired tissue perfusion)
                                                                          No


                                                          Identify and treat                   b
                                                          reversible causes            12 Lead ECG




                                                       Beta-blocker IV
                                                      Metroprolol 5 mg IV            LVEF < 40% or
                                                        over 1–2 min                   unknown
                                                       Can repeat × 3 b




                                               Amiodarone 150 or 300 mg       Procainamide 20–50 mg/min
                                               IV over 10 min then repeat        up to 17 mg/kg then
                                                150 if necessary ± infusion
                                                       or                          1–4 mg/min
                                               Lidocaine 1 to 1.5 mg/kg ×              or
                                                   1 then infusion            Sotalol 1.5 mg/kg over 5 min




                                                                  Synchronized
                                                                  Cardioversion
                                                                   120–200 J a

                 FIGURE 36-3.  Management algorithm for sustained monomorphic ventricular tachycardia.
                 a For monophasic start at least 100 J and increase dose if necessary.
                 b Recent guidelines do suggest that adenosine can be used in stable wide complex tachycardia for diagnosis and treatment. Once stabilized then will need determination of long-term antiarrhythmic medication and/or ICD.








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