Page 2640 - Hematology_ Basic Principles and Practice ( PDFDrive )

Chapter 162 Resources for the Hematologist e21

TABLE
162.21 Plasma Levels of Immunoglobulin A in Males and Females, by Age
Male Female
Age Number mg/dL g/L Number mg/dL g/L
Soldin et al (1996) a
1–30 days 61 1–20 0.01–0.20 56 1–19 0.01–0.19
31–182 days 52 7–56 0.07–0.56 60 1–59 0.01–0.59
183–365 days 37 9–107 0.09–1.07 23 15–90 0.15–0.90
1–3 years 105 18–171 0.18–1.71 127 25–141 0.25–1.41
4–6 years 138 60–231 0.60–2.31 135 47–206 0.47–2.06
7–9 years 111 77–252 0.77–2.52 105 41–218 0.41–2.18
10–12 years 104 61–269 0.61–2.69 115 73–239 0.73–2.39
13–15 years 104 42–304 0.42–3.04 118 82–296 0.82–2.96
16–18 years 112 89–314 0.89–3.14 100 90–322 0.90–3.22
Male/Female
Age mg/dL g/L
Lockitch et al (1988) b
0–12 months 0–100 0.00–1.00
1–3 years 24–121 0.24–1.21
4–6 years 33–235 0.33–2.35
7–9 years 41–368 0.41–3.68
10–11 years 64–246 0.64–2.46
12–13 years 70–432 0.70–4.32
14–15 years 57–300 0.57–3.00
16–19 years 74–419 0.74–4.19
a From Soldin SJ, Bailey J, Beatey J, et al: Pediatric reference ranges for immunoglobulins G, A and M on the Behring nephelometer. Clin Chem 42:S308, 1996.
b From Lockitch G, Halstead AC, Quigley G, et al: Age- and sex-specific pediatric reference intervals: Study design and methods illustrated by measurement of serum
proteins with the Behring LN nephelometer. Clin Chem 34:1618, 1988. Results are 0.025th to 0.975th fractiles.

TABLE Immunoglobulin E in Males and Females, by Age
162.22
Age Females Males Age Females Males
Soldin et al (1995) a Lindberg and Arroyave (1996) d
0–12 months <8 KIU/L <12 KIU/L <1 year 0–6.6 IU/mL
1–3 years <28 KIU/L <90 KIU/L 1–2 years 0–20.0 IU/mL
4–10 years <137 KIU/L <163 KIU/L 2–3 years 0.1–15.8 IU/mL
11–18 years <398 KIU/L <179 KIU/L 3–4 years 0–29.2 IU/mL
Soldin et al (1995) b 4–5 years 0.3–25.0 IU/mL
0–12 months 0–20 KIU/L 2–24 KIU/L 5–6 years 0.2–17.6 IU/mL
1–3 years 2–55 KIU/L 2–149 KIU/L
6–7 years 0.2–13.1 IU/mL
4–10 years 8–279 KIU/L 4–249 KIU/L
7–8 years 0.3–46.1 IU/mL
11–15 years 5–295 KIU/L 7–280 KIU/L
8–9 years 1.8–60.1 IU/mL
16–18 years 7–698 KIU/L 5–268 KIU/L 9–10 years 3.6–81.0 IU/mL
Ownby et al (1991) c
Cord blood 0.02–2.08 KIU/L 10–11 years 8.0–95.0 IU/mL
11–12 years 1.5–99.7 IU/mL
12–13 years 3.9–83.5 IU/mL
13–16 years 3.3–188.0 IU/mL
a From Soldin SJ, Lenherr S, Kumar A: Pediatric reference ranges for IgE. Clin Chem 41:S92, 1995.
b From Soldin SJ, Morales A, Albalos F, et al: Pediatric reference ranges on the Abbott IMx for FSH, LH, prolactin, TSH, T4, T3, free T3, T-uptake, IgE, and ferritin. Clin
Biochem 28:603, 1995. Study was based on hospitalized patients. Values represent 2.5th to 97.5th percentiles.
c From Ownby DR, Johnson CC, Peterson EL: Maternal smoking does not influence cord serum IgE or IgD concentrations. J Allergy Clin Immunol 88:555, 1991. Values
constitute 95% of the measured samples.
d From Lindberg RE, Arroyave C: Levels of IgE in serum from normal children and allergic children as measured by an enzyme immunoassay. J Allergy Clin Immunol
78:614, 1986. Three hundred forty-six nonatopic children were selected for study by enzyme-linked immunosorbent assay methodology.