Page 745 - First Aid for the USMLE Step 1 2020, Thirtieth edition [MedicalBooksVN.com]_Neat

Rapid Review ` ClassiC/relevant treatments Rapid Review ` ClassiC/relevant treatments SeCTiON iii 701

ConDition Common treatment(s) PaGe
Chronic myelogenous leukemia Imatinib 433
Acute promyelocytic leukemia (M3) All-trans retinoic acid, arsenic trioxide 432

Drug of choice for anticoagulation in pregnancy or renal Low-molecular-weight heparin 436
failure
Heparin reversal Protamine sulfate 436
Immediate anticoagulation Heparin 436
Long-term anticoagulation Warfarin, dabigatran, rivaroxaban and apixaban 436,
437
Warfarin reversal Fresh frozen plasma (acute), vitamin K (non-acute) 436
Cyclophosphamide-induced hemorrhagic cystitis Mesna 441
HER2/neu ⊕ breast cancer Trastuzumab 443

Osteoporosis Calcium/vitamin D supplementation (prophylaxis); 462
bisphosphonates, PTH analogs, SERMs, calcitonin,
denosumab (treatment)
Osteomalacia/rickets Vitamin D supplementation 463

Chronic gout Xanthine oxidase inhibitors (eg, allopurinol, febuxostat); 467
pegloticase; probenecid
Acute gout attack NSAIDs, colchicine, glucocorticoids 467
Neural tube defect prevention Prenatal folic acid 491
Migraine Abortive therapies (eg, sumatriptan, NSAIDs); prophylaxis 518
(eg, propranolol, topiramate, CCBs, amitriptyline)
Multiple sclerosis Disease-modifying therapies (eg, β-interferon, 523
natalizumab); for acute flares, use IV steroids
Tonic-clonic seizures Levetiracetam, phenytoin, valproate, carbamazepine 544
Absence seizures Ethosuximide 544
Trigeminal neuralgia (tic douloureux) Carbamazepine 544

Malignant hyperthermia Dantrolene 551
Anorexia Nutrition, psychotherapy, SSRIs 567
Bulimia nervosa SSRIs 567
Alcoholism Disulfiram, acamprosate, naltrexone, supportive care 571
ADHD Methylphenidate, amphetamines, CBT, atomoxetine, 572
guanfacine, clonidine
Alcohol withdrawal Long-acting benzodiazepines 572
Bipolar disorder Mood stabilizers (eg, lithium, valproic acid, 572
carbamazepine), atypical antipsychotics
Depression SSRIs (first-line) 572

Generalized anxiety disorder SSRIs, SNRIs (first line); buspirone (second line) 572
Schizophrenia (positive symptoms) Typical and atypical antipsychotics 573
Schizophrenia (negative symptoms) Atypical antipsychotics 573

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